参精颗粒治疗小儿反复呼吸道感染气阴两虚型的临床研究

发布时间：2018-04-28 03:39

本文选题：反复呼吸道感染 + 参精颗粒　；参考：《中国中医科学院》2012年硕士论文

【摘要】：目的：评价参精颗粒治疗小儿反复呼吸道感染气阴两虚型的有效性和安全性。方法：将110例气阴两虚型反复呼吸道感染患儿随机分为两组,其中治疗组74例,对照组36例。治疗组给予参精颗粒治疗,对照组给予匹多莫德口服液治疗,疗程均为1个月,观察半年。结果：治疗组完成观察70例,对照组完成35例。治疗前两组患儿在性别、年龄构成及发病情况、症状、体征方面无明显差异,具有可比性。治疗结束后6个月,治疗组及对照组总积分、中医证候与治疗前比较,均有显著差异(P0.05)；、治疗组临床疗效总有效率为95.71%,对照组临床疗效总有效率为82.86%,两组疗效无显著差异(P0.05)；治疗组中医证候疗效总有效率为91.43%,对照组中医证候疗效总有效率为74.29%,两组疗效有显著差异(P0.05)；治疗组纳呆、便秘与对照组比较,积分减少有显著差异(P0.05)；治疗组多汗与对照组比较,积分减少无显著差异(P0.05)。治疗组未发现任何不良反应,对照组有1例对试验药物过敏。结论：参精颗粒治疗小儿反复呼吸道感染气阴两虚型,能有效控制呼吸道感染反复发作,减少发病次数,降低发病等级,缩短病程,并能很好的改善中医证候,是治疗小儿反复呼吸道感染气阴两虚型的安全、有效方剂。
[Abstract]:Objective: to evaluate the efficacy and safety of Shenjing granule in the treatment of deficiency of qi and yin in children with recurrent respiratory tract infection. Methods: 110 children with recurrent respiratory tract infection with deficiency of Qi and Yin were randomly divided into two groups: treatment group (n = 74) and control group (n = 36). The treatment group was treated with Shenjing granule, while the control group was treated with pidomod oral liquid for 1 month. Results: 70 cases were observed in the treatment group and 35 cases in the control group. There were no significant differences in sex, age composition, incidence, symptoms and signs between the two groups before treatment. Six months after the end of treatment, the total score of treatment group and control group, TCM syndromes were compared with those before treatment. The total effective rate of the treatment group was 95.71, the total effective rate of the control group was 82.86, there was no significant difference between the two groups (P 0.05), the total effective rate of TCM syndrome was 91.43 in the treatment group, and the total effective rate in the control group was 82.86.The total effective rate of TCM syndromes was 91.43 in the treatment group and 82.86 in the control group. The rate was 74.29. There was a significant difference between the two groups (P 0.05). Compared with the control group, the score of constipation was significantly lower than that of the control group (P 0.05), while that of hyperhidrosis in the treatment group was not significantly different from that of the control group (P 0.05). No adverse reactions were found in the treatment group and 1 case in the control group was allergic to the test drug. Conclusion: Shenjing granule can effectively control recurrent respiratory tract infection in children with deficiency of Qi and Yin, reduce the number of cases, reduce the grade of disease, shorten the course of disease, and improve the syndrome of traditional Chinese medicine. It is a safe and effective prescription for treating recurrent respiratory tract infection in children with deficiency of qi and yin.
【学位授予单位】：中国中医科学院
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R272

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