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孕期宫内环境与新生儿出生情况的相关性研究

发布时间:2018-04-28 21:38

  本文选题:宫内环境 + BMI ; 参考:《浙江大学》2012年硕士论文


【摘要】:目的:探讨浙江省4个市(永康市、湖州市、宁海市、绍兴市)孕产妇孕前BMI,孕期高龄、吸烟、饮酒等危险因素,家族肥胖、高血压、糖尿病等代谢综合征史,孕期营养情况和孕晚期血生化指标对新生儿出生体重、新生儿脐血生化指标的影响,了解孕期宫内环境对新生儿的影响。 方法:选取2010年1月1日至2011年4月1日在永康市、湖州市、宁海市及绍兴市妇幼保健院行产前检查并于该院分娩的32-37周孕妇共1325例,对相关家庭背景、孕前BMI、孕期相关危险因素、孕期膳食营养情况、分娩情况、新生儿体重及孕晚期血液及脐血生化指标等数据进行整理及统计分析。 结果:1325例孕产妇每日摄入的碳水化合物(166.0±61.4)g及蛋白质(52.7±22.2)g明显低于推荐量(P0.01);每日摄入的脂肪(41.0±24.2)g高于推荐摄入量(P0.05)。新生儿体重、脐血ApoAl、C肽以及胰岛素水平与母孕前BMI正相关。脐血脂蛋白a高于平均值的孕母脂肪摄入量高(P0.05);脐血胰岛素及C肽高于平均值的孕母能量及碳水化合物摄入量高(P0.01)。高出生体重组母血甘油三酯水平、胰岛素水平及脐血胰岛素水平高于低出生体重组及正常出生体重组(P0.05);低出生体重组脐血ApoAl与HDL水平低于高出生体重组及正常出生体重组(P0.01)。 结论:浙江省4个市孕产妇孕期膳食营养不平衡;出生体重与孕前BMI、孕晚期母血甘油三酯、胰岛素水平正相关;低出生体重儿脐血HDL水平偏低,高出生体重儿脐血胰岛素水平偏高。
[Abstract]:Objective: to study the history of metabolic syndrome of pregnant women in 4 cities (Yongkang, Huzhou, Ninghai, Shaoxing) in Zhejiang province, such as pregnancy, old age during pregnancy, smoking, drinking, family obesity, hypertension, diabetes, etc. Effects of nutritional status during pregnancy and biochemical indexes of blood in late pregnancy on birth weight and umbilical blood biochemical indexes of newborns, and to understand the influence of intrauterine environment during pregnancy on newborns. Methods: from January 1, 2010 to April 1, 2011, 1325 pregnant women in Yongkang, Huzhou, Ninghai and Shaoxing maternal and child health hospitals were selected and delivered in the hospital. The data of pre-pregnancy BMI, risk factors during pregnancy, dietary nutrition during pregnancy, delivery, weight of newborn and biochemical indexes of blood and umbilical blood in the third trimester of pregnancy were collected and analyzed statistically. Results the daily intake of carbohydrate and protein were 166.0 卤61.4g and 52.7 卤22.2g / day in 1: 1325 pregnant women, and the daily intake of fat was 41.0 卤24.2g / day, which was significantly lower than that of the recommended dose (P0.05g). Neonatal weight, umbilical cord blood ApoAlN C peptide and insulin levels were positively correlated with maternal pre-pregnancy BMI. The maternal fat intake of umbilical cord blood was higher than the average of serum lipoprotein a and the maternal energy and carbohydrate intake of umbilical cord blood insulin and C-peptide were higher than that of the average maternal fat intake. The levels of triglyceride, insulin and cord blood insulin in high birth weight group were higher than those in low birth weight group and normal birth weight group (P 0.05), and the levels of ApoAl and HDL in low birth weight group were lower than those in high birth weight group and normal birth weight group. Conclusion: pregnant women in 4 cities of Zhejiang Province have unbalanced dietary nutrition during pregnancy, birth weight is positively correlated with pre-pregnancy BMI, serum triglyceride and insulin levels in late trimester, HDL level in umbilical cord blood of low birth weight infants is lower than that in infants with low birth weight. Cord blood insulin level was higher in high birth weight infants.
【学位授予单位】:浙江大学
【学位级别】:硕士
【学位授予年份】:2012
【分类号】:R722.1

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