初发1型糖尿病患儿酮症酸中毒的调查

发布时间：2018-05-08 02:31

  本文选题：型糖尿病 + 酮症酸中毒　； 参考：《中国当代儿科杂志》2017年10期

【摘要】：目的调查初发1型糖尿病患儿酮症酸中毒(DKA)的发生情况。方法以224例初发1型糖尿病患儿为研究对象,进行回顾性分析,分为DKA组和未合并DKA组,各112例。DKA组患儿根据年龄分为≥5岁组(65例)和5岁组(47例),并根据酸中毒情况分为轻度(26例)、中度(29例)、重度(57例)3组。分析DKA发生的影响因素以及不同年龄DKA患儿的临床及实验室特点。结果 224例初发1型糖尿病患儿中最常见的症状为多饮(86.2%)、多尿(78.6%)及体重下降(57.1%)。与未合并DKA患儿比较,DKA组5岁、低收入、父母教育程度高中及以下所占的比例均较高,随机血糖、Hb A1C水平较高,pH、HCO_3~-及C肽水平更低,差异均具有统计学意义(P0.05)。≥5岁组与5岁组的轻、中、重度DKA所占比例的差异无统计学意义(P0.05)。与5岁组相比,≥5岁组DKA患儿的症状持续时间较长,随机血糖较低,HbA1C、C肽水平较高,差异具有统计学意义(P0.05)。结论 1型糖尿病患儿DKA发生率高,DKA的发生与年龄、父母文化程度及家庭收入有关。
[Abstract]:Objective to investigate the incidence of ketoacidosis in children with type 1 diabetes mellitus. Methods 224 children with primary type 1 diabetes mellitus were retrospectively analyzed and divided into two groups: DKA group and uncomplicated DKA group. 112 cases of DKA group were divided into 5 years old group (65 cases) and 5 years old group (47 cases). According to the condition of acidosis, they were divided into 3 groups. To analyze the influencing factors of DKA and the clinical and laboratory characteristics of DKA children of different ages. Results the most common symptoms of 224 children with type 1 diabetes were polydipsia (86.2) and diuresis (78.6) and weight loss (57.1%). In DKA group, the proportion of children aged 5 years old, low income, parents' education level and HbA1C level were higher than those in children without DKA, and the levels of HbA1C and C-peptide were lower in DKA group than those in non-DKA group, and the levels of HbA1C and HbA1C were lower in DKA group than those in DKA group. The difference was statistically significant (P < 0.05). There was no significant difference in the proportion of severe DKA between the group of 鈮，

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