延边小学生血脂体质量指数与代谢综合征的关系
本文选题:脂肪酸类 + 非酯化 ; 参考:《中国学校卫生》2017年07期
【摘要】:目的探讨延边地区汉族和朝鲜族小学生血清游离脂肪酸(FFA)与体质量指数(BMI)对代谢综合征(MS)患病危险的关联性,为早期筛选儿童青少年MS高危人群提供依据。方法分别于2012年7月15—18日和2013年7月16—21日,在吉林省延边朝鲜族自治州选择5所小学校,采用整群抽样的方法,共抽取5 747名小学生(汉族3 736名,朝鲜族2 011名)作为研究对象,全部测量身高、体重、腰围和血压,并检测清晨空腹血清三酰甘油、高密度脂蛋白胆固醇、血糖、FFA。结果调整年龄和性别的协方差分析结果显示,汉族学生MS组和正常组FFA平均水平分别为(22.72±2.72)和(21.09±2.60)μmol/L,朝鲜族学生分别为(23.49±1.64)和(21.95±1.63)μmol/L;汉族学生MS组和正常组BMI平均水平分别为(25.68±3.58)和(16.98±2.89)kg/m~2,朝鲜族学生分别为(23.11±3.63)和(17.86±3.05)kg/m~2,汉族和朝鲜族学生MS组FFA和BMI平均水平均高于正常组学生(P值均0.01),且不同民族学生MS患病水平均随着FFA和BMI水平的增加而增加(P值均0.01)。调整了年龄和性别因素后,Logistic回归分析显示,汉族学生FFA水平第四分位组MS患病危险是第一分位组的2.693倍,朝鲜族学生为12.132倍;汉族学生超重组和肥胖组的MS患病危险是正常组的19.646和223.666倍,朝鲜族学生分别为4.860和19.204倍。FFAP_(75)且BMI超重及肥胖组的汉族(OR=172.524,95%CI=60.288~493.705)和朝鲜族(OR=79.188,95%CI=35.728~175.513)学生MS患病危险升高,且均高于单纯FFAP_(75)组和BMI超重及肥胖组。结论延边地区学生FFA和BMI均与MS患病密切相关,FFA升高合并超重及肥胖学生MS患病危险性较高。FFA水平升高可以预测MS的患病危险,并且对于朝鲜族学生的预测作用强于汉族学生。
[Abstract]:Objective to investigate the association between serum free fatty acid (FFAA) and body mass index (BMI) in primary school students of Han nationality and Korean nationality in Yanbian area, and to provide evidence for early screening of high risk population of MS among children and adolescents. Methods from 15 to 18 July 2012 and from 16 to 21 July 2013, 5 primary schools were selected from Yanbian Korean Autonomous Prefecture of Jilin Province. A total of 5 747 pupils (3 736 Han nationality) were selected by cluster sampling. The height, weight, waist circumference and blood pressure were measured, and fasting serum triglyceride, high density lipoprotein cholesterol and FFAs were measured. Results the covariance analysis, adjusted for age and sex, showed that The average FFA levels of MS group and normal group were 22.72 卤2.72 渭 mol / L and 21.09 卤2.60 渭 mol / L, those of Korean students were 23.49 卤1.64) and 21.95 卤1.63 渭 mol / L respectively; the average BMI levels of MS group and normal group of Han nationality students were 25.68 卤3.58) and 16.98 卤2.89 kg 路mm2; Korean students were 23.11 卤3.63 渭 mol / L and 17.86 卤3.05 kg 路m-2; Han and Korean nationality students were 23.11 卤3.63 渭 mol / L and 17.86 卤3.05 渭 mol / L, respectively. The average levels of FFA and BMI in MS group were higher than those in normal group (P < 0.01), and the prevalence level of MS in students of different nationalities increased with the increase of FFA and BMI levels. After adjusting for age and sex, logistic regression analysis showed that the risk of MS in the fourth quartile group of Han nationality students was 2.693 times that of the first one group, and that of Korean students was 12.132 times. The risk of MS in Han nationality students was 19.646 and 223.666 times higher than that in the normal group, and the risk of MS in Korean students was 4.860 and 19.204 times. FFAPP 75), and the risk of MS in Han nationality students in overweight and obese BMI group was 60.28895 and 493.705), and the risk of MS in Korean students was higher than that in the Korean nationality group (Or79.18895CII 35.728175.513), and in the overweight and obese group of Han nationality, the risk of MS in Han nationality students was higher than that in the normal group (4.860 and 19.204 times respectively), and in the overweight and obese group of Han nationality, the risk of MS was increased. All of them were higher than those of FFAPD 75) group and BMI overweight and obesity group. Conclusion both FFA and BMI are closely related to the prevalence of MS in Yanbian area. The higher risk of MS in students with overweight and obesity can predict the risk of MS, and the predictive effect on Korean students is stronger than that of Han students.
【作者单位】: 延边大学附属医院;延边大学医学院;
【基金】:国家自然科学基金项目(81160349,81260138) 吉林省教育厅基金项目(2013-25)
【分类号】:R725.8
【参考文献】
相关期刊论文 前10条
1 曹荟哲;哈小琴;李雪雁;徐倩;白燕青;曾通旭;;游离脂肪酸致胰岛素抵抗的分子机制[J];解放军医学杂志;2017年01期
2 陈效琴;任静;;游离脂肪酸、胰岛素抵抗与代谢综合征相关因素的关系[J];检验医学;2016年07期
3 王迪;刘亚军;黄慧妍;刘俊茹;王星;范冬梅;张悦;曹宏伟;尹福在;刘博伟;;青年游离脂肪酸水平与代谢综合征的相关性研究[J];河北医药;2016年06期
4 余仁强;周勤;马路一;;儿童肥胖与心血管疾病危险因素的关系研究进展[J];新乡医学院学报;2016年01期
5 刘风华;胡琼;王李洁;;肥胖患者血清游离脂肪酸与代谢紊乱关系的研究[J];中国卫生检验杂志;2015年20期
6 陈效琴;俞安清;张博林;赵诤;蹇国;何平;伏攀;任静;;肥胖及腹型肥胖人群的血清游离脂肪酸水平与胰岛素抵抗的关系研究[J];检验医学与临床;2015年19期
7 马军;;儿童代谢综合征研究进展[J];中国儿童保健杂志;2013年05期
8 王文鹏;张美仙;席波;;儿童 青少年代谢综合征流行趋势及特征[J];山西医药杂志;2012年07期
9 于冬梅;赵丽云;朴建华;张坚;胡小琪;付萍;;8省市儿童青少年代谢综合征流行现况及其主要影响因素[J];中国健康教育;2012年06期
10 戴晓岚;;代谢综合征的研究新进展[J];中国慢性病预防与控制;2011年04期
相关硕士学位论文 前1条
1 杨磊磊;叉头框C2-512C>T基因多态性和游离脂肪酸与代谢综合征的相关性研究[D];天津医科大学;2007年
【共引文献】
相关期刊论文 前10条
1 程绪婷;王宏;袁保诚;管佩钰;王翎懿;;2014年重庆城区儿童青少年代谢综合征及家庭影响因素[J];卫生研究;2017年04期
2 李医华;全振喜;文海燕;方今女;;延边小学生血脂体质量指数与代谢综合征的关系[J];中国学校卫生;2017年07期
3 牛学虹;;精神分裂症与代谢综合征相关性研究进展[J];中国处方药;2017年07期
4 顾科萍;王亚平;余伟;张敏;龚梦姣;姜宇海;;应用ROC曲线分析冠心病患者中游离脂肪酸的临床应用价值[J];检验医学;2017年05期
5 庄欣;杨洁;林慧娟;;补肾通络法干预代谢综合征及其对TLR4/NF-κB炎性信号通路影响的临床研究[J];江苏中医药;2017年04期
6 李彬;张姝s,
本文编号:1859624
本文链接:https://www.wllwen.com/yixuelunwen/eklw/1859624.html