社区获得性肺炎住院患儿混合感染研究

发布时间：2018-05-12 09:07

本文选题：儿童 + 社区获得性肺炎　；参考：《中国实用儿科杂志》2017年09期

【摘要】：目的了解社区获得性肺炎(CAP)住院患儿混合感染情况。方法对2015年1月至12月期间于苏州大学附属儿童医院呼吸科住院治疗的CAP患儿进行多种病原联合检测。结果 846例CAP住院患儿中647例(76.5%)检出病原,其中单一病原感染354例(41.84%),混合感染293例(34.63%)。6个月、~1岁、~3岁、~5岁、5岁年龄组混合感染率分别为24.2%、43.5%、43.8%、36.8%、27.3%。6个月和~1岁组患儿以病毒+细菌混合感染最常见,~3岁患儿以病毒+肺炎支原体(MP)混合感染常见,~5岁以MP+细菌混合感染常见,5岁以MP+病毒混合感染常见。病毒混合细菌感染以鼻病毒(h RV)+流感嗜血杆菌(18.6%)多见;MP混合病毒感染中以h RV(62.1%)为主;MP混合细菌感染中以肺炎链球菌(67.8%)多见。单一病原感染与混合感染CAP的临床表现、并发症发生率、入PICU的比例及住院时间相比均无明显差异。结论 CAP住院患儿中混合感染占有一定的比例,以~1岁及~3岁年龄组多见;不同年龄组混合感染的组合有所不同;混合感染的CAP无特异性表现,并不加重病情。
[Abstract]:Objective to investigate the mixed infection in hospitalized children with community acquired pneumonia (CAP). Methods from January to December 2015, children with CAP who were hospitalized in Department of Respiratory, affiliated Children's Hospital of Suzhou University were tested for multiple pathogens. Results of the 846 hospitalized children with CAP, 647 were found to be pathogenic. Among these cases, 354 cases were single pathogen infection, and 293 cases were mixed infection with 34.63%. The mixed infection rate of 6 months old, 1 year old, 3 year old, 5 year old and 5 year old group was 24.223.535 and 43.8%, respectively. The infection rate was 27.3.6 months old and 1 year old group. The most common infection rate was virus infection in the lung of 3 years old children. Mixed infection of Mycoplasma phlogistic (MPM) was common in 5 years old and MP virus was common in 5 years of age with mixed infection of MP bacteria. The mixed bacterial infection of rhinovirus (HRV) and Haemophilus influenzae (18.6) was more common in the mixed virus infection of MP than that of hRV (62.1) and Streptococcus pneumoniae (67.8%) in the mixed bacterial infection. There was no significant difference in clinical manifestation, incidence of complications, proportion of PICU entry and length of hospitalization between single pathogen infection and mixed infection CAP. Conclusion the proportion of mixed infection in CAP hospitalized children is more than that in the age group of 1 and 3 years old, the combination of mixed infection is different among different age groups, and the CAP of mixed infection has no specific manifestation and does not aggravate the disease.
【作者单位】：苏州大学附属儿童医院呼吸科;苏州大学附属儿童医院检验科;
【基金】：国家自然科学基金面上项目(81573167) 苏州市科技发展计划(SYS201436)
【分类号】：R725.6

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