福建省家庭户盐碘含量与学龄儿童甲状腺容积关系的横断面研究

发布时间：2018-05-22 15:54

本文选题：甲状腺容积 + 碘盐　；参考：《中国地方病防治杂志》2017年05期

【摘要】：目的评价2011年、2014年和2016年福建省碘缺乏病监测中不同盐碘含量对学龄儿童甲状腺容积分布的影响。方法 2011年和2014年福建省碘缺乏病监测采用以人口比例概率抽样法(PPS)分别抽取了1 219名和1 507名8-10岁儿童,而2016年以县级为单位采用分层抽样法抽取了6 312名8-10岁儿童;对抽中的儿童进行家庭户食用盐样和尿样采集以及甲状腺B超的测量。采用直方图和箱式图对甲状腺容积分布进行分析,计算偏度和峰度进行甲状腺容积正态性检验。结果家庭户食用盐碘中位数从2011年的29.30 mg/kg降低到2016年的23.20 mg/kg;2011年、2014年和2016年8-10岁儿童尿碘中位数分别为223.00、154.30和187.20μg/L;2011年、2014年和2016年甲状腺容积中位数(M)和四分数间距(IQR)分别为3.09 ml和1.21 ml、2.80 ml和1.10 ml、3.10 ml和1.20 ml;2011年、2014年、2016年甲状腺容积峰度和偏度分别为8.37和125.94、1.19和3.41、1.64和6.25。结论随着盐碘含量下降,学龄儿童尿碘中位数降低到适宜状态,同时甲状腺容积分布对称性提高。
[Abstract]:Objective to evaluate the effect of different salt iodine content on thyroid volume distribution in school-age children in Fujian Province in 2011, 2014 and 2016. Methods in 2011 and 2014, 1 219 and 1 507 children aged 8 to 10 years were selected from IDD surveillance in Fujian Province, respectively, and 6 312 children aged 8 to 10 years were sampled by stratified sampling at county level in 2016. The samples of salt and urine were collected and the thyroid B-ultrasound was measured. The thyroid volume distribution was analyzed by histogram and box diagram, and the deviation and kurtosis were calculated to test the normal thyroid volume. Results the median salt iodine consumption decreased from 29.30 mg/kg in 2011 to 23.20 mg / kg in 2016; the median urinary iodine in children aged 8-10 in 2011 and 2016 was 223.00154.30 and 187.20 渭 g / L, respectively; in 2011, 2014 and 2016, the median thyroid volume was M) and the four-fractional interval was measured. It was 3.09 ml and 1.21 ml 2.80 ml and 1.10 ml 3.10 ml and 1.20 ml; in 2011, 2014, the thyroid volume kurtosis and deviation in 2016 were 8.37 and 125.94% 1.19 and 3.41 卤1.64 and 6.25, respectively. Conclusion with the decrease of salt iodine content, the median of urinary iodine in school-age children decreased to a suitable state, and the symmetry of thyroid volume distribution increased.
【作者单位】：福建省疾病预防控制中心;福建医科大学公共卫生学院;
【基金】：中央补助地方公共卫生专项资金地方病防治项目(2011、2014和2016)
【分类号】：R725.9

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