大连地区121例过敏性疾病患儿皮肤点刺试验结果分析

发布时间：2018-05-31 17:56

  本文选题：过敏性疾病 + 儿童　； 参考：《大连医科大学》2012年硕士论文

【摘要】：目的：了解大连地区引起儿童过敏性疾病的主要致敏原及其在不同年龄、性别、季节时可能存在的差别。探讨常见儿童过敏性皮肤病与致敏原种类的关系及是否合并过敏性鼻炎、哮喘与致敏原种类的关系。 方法：采用德国默克公司生产的变应原点刺液，对2006年9月-2009年8月我科门诊121名过敏性疾病患儿，详细询问病史、既往史，初步诊断为过敏性疾病，并进行皮肤点刺试验(SPT)。统计学上应用SPSS11.5统计软件，统计方法为卡方检验及Fisher确切概率法， P0．05为差异有统计学意义，，P0．01为差异有非常显著意义。 结果：其结果进行回顾性分析，121例患儿出现阳性反应的92例，阳性率76%；居于前5位的过敏原有粉尘螨（47.9%）、屋尘螨（45.5%）、须发癣菌（29.8%）、霉菌Ⅱ（28.1%）、霉菌Ⅰ（24.8%）。57.8%的患儿出现3种以上阳性反应。干草尘埃阳性率与性别有关；牛奶类阳性率与年龄有关；乳胶类、番茄、鸡肉、小麦粉、欧芹、干辣椒、香菜阳性率与发病季节有关。干草尘埃阳性率荨麻疹及湿疹组相当，明显高于皮炎组；干辣椒和小麦粉阳性率荨麻疹组明显低于皮炎和湿疹组。有过敏性鼻炎或哮喘病史组所有过敏原阳性率均高于单纯皮肤损害组，其中粉尘螨、屋尘螨、须发癣菌、霉菌Ⅱ、蚌类、干辣椒、小麦粉、鸡蛋、海鱼类、柑橘、花生有统计学意义。 结论：粉尘螨、屋尘螨、须发癣菌、霉菌Ⅱ、霉菌Ⅰ为大连地区患过敏性疾病儿童的主要过敏原，吸入性过敏原占主要地位，有遗传过敏体质患儿的过敏原阳性率明显增高，因此，为过敏性疾病患儿临床的诊断、治疗和预防提供了理论依据。
[Abstract]:Objective: to investigate the main allergens and their possible differences in age, sex and season of allergic diseases in children in Dalian area. To investigate the relationship between allergic dermatoses and allergen types in children and whether they are associated with allergic rhinitis, asthma and allergen species. Methods: 121 children with allergic diseases in our department from September 2006 to August 2009 were asked about the history, past history, preliminary diagnosis of allergic diseases and skin prick test. Statistical application of SPSS11.5 statistical software, statistical methods for chi-square test and Fisher exact probability method, P0.05 for the difference was statistically significant (P0.01). Results: the results were analyzed retrospectively in 92 cases of 121 children with positive reaction, the positive rate was 76%, 47.9% of the first 5 allergies were dust mite, 45.5% of house dust mite, 29.88% of Tinea fibrosus, 28.1% of mildew 鈪

本文编号：1960771