以中枢神经症状为首发表现的儿童原发性干燥综合征1例并文献复习

发布时间：2018-06-13 08:01

本文选题：原发性干燥综合征 + 中枢神经　；参考：《临床儿科杂志》2017年10期

【摘要】：目的探讨以中枢神经系统受累为首发表现的儿童原发性干燥综合征(p SS)的诊断和治疗。方法回顾分析1例以发热、头痛起病的11岁男性p SS患儿的临床资料,并复习相关文献。结果患儿经自身抗体、唇腺活检和眼科检查确诊p SS,给予免疫抑制治疗后好转。文献报道,儿童p SS发病率低,其中以神经系统受累为主要表现的更少,而头痛是最常发生的中枢神经症状。糖皮质激素和免疫抑制剂的应用有助于改善病情。结论儿童p SS中枢神经受累症状不典型,自身抗体和唇腺活检有助于诊断。
[Abstract]:Objective to investigate the diagnosis and treatment of primary Sjogren's syndrome (PSS) in children with central nervous system involvement. Methods the clinical data of 11-year-old male patients with PSS caused by fever and headache were retrospectively analyzed and the related literatures were reviewed. Results PSS was confirmed by autoantibody, labial gland biopsy and ophthalmology, and improved after immunosuppressive therapy. It is reported that the incidence of PSS in children is low, in which nervous system involvement is the main manifestation, and headache is the most common symptom of central nervous system. The use of glucocorticoids and immunosuppressants can help improve the condition. Conclusion the symptoms of central nervous system involvement in children with PSS are atypical. Autoantibodies and labial gland biopsy are helpful in diagnosis.
【作者单位】：上海交通大学医学院附属上海儿童医学中心;
【分类号】：R725.9

【相似文献】