中药穴位敷贴结合膏方治疗小儿哮喘缓解期的临床研究

发布时间：2018-06-15 09:53

本文选题：小儿哮喘 + 缓解期　；参考：《南京中医药大学》2012年硕士论文

【摘要】：研究目的：哮喘是小儿时期常见的肺系疾病,有反复发作、迁延难愈的特点,对儿童健康危害极大,而在哮喘缓解期对患儿进行积极治疗,以减轻和减少哮喘的发作是小儿哮喘治疗的关键。本文通过观察治疗前后患儿哮喘的发作次数、发作时哮鸣音、发作时喘息、感冒次数、鼻塞鼻痒及面色、汗出、气促及大便、舌象等指标的变化,客观评价中药穴位敷贴结合口服中药膏方治疗小儿哮喘缓解期的临床疗效。研究方法：选取符合诊断标准的哮喘缓解期患儿60例,以2：1的比例随机分为试验组和对照组,最终收取试验组40例,对照组20例。治疗前两组患儿在性别、年龄、体重及病情方面,差异无统计学意义(P0.05),具有可比性。试验组用中药穴位敷贴结合口服中药膏方治疗,对照组予单纯口服中药膏方治疗。两组均治疗1个疗程,随访3个月。疗程结束后,比较两组患儿主症、次症积分及中医证候总积分的改善情况,评价两种不同治疗方案治疗小儿哮喘缓解期的临床疗效。研究结果：共完成研究观察病例数共60例,其中治疗组40例,对照组20例。统计结果如下： 1.治疗后两组患儿主症改善：试验组在发作时哮鸣音及感冒发作次数方面,明显优于对照组(P0.01)；在改善哮喘发作时喘息方面,试验组优于对照组(P0.05)；在鼻塞鼻痒方面,与对照组疗效相似(P0.05)。 2.治疗后两组患儿次症改善：试验组与对照组疗效相似(P0.05)。 3.疗效评价：试验组临床痊愈、显效、有效、无效例数为8、16、14、2,对照组临床痊愈、显效、有效、无效例数为2、4、10、4,临床痊愈率、总有效率分别为治疗组20.0%、95.0%,对照组为10.0%、80.0%,差异有统计学意义(P0.05),试验组优于对照组。 4.试验组和对照组在治疗过程和随访时,均未发现副作用。结论：中药穴位敷贴结合中药膏方和单纯中药膏方口服治疗小儿哮喘缓解期均取得很好疗效,前者疗效优于后者,临床使用安全性好。
[Abstract]:Objective: asthma is a common pulmonary disease in childhood. It has the characteristics of repeated attacks and prolonged and difficult to heal. It is harmful to children's health, but the children are actively treated during the remission period of asthma. To alleviate and reduce the attack of asthma is the key to the treatment of asthma in children. The changes of asthma attacks, wheezing, colds, nasal congestion, itching and complexion, sweating, shortness of breath and stool, tongue appearance were observed before and after treatment. Objective to evaluate the clinical efficacy of acupoint application combined with oral ointment in the remission of childhood asthma. Methods: sixty children with asthma in remission period who met the diagnostic criteria were randomly divided into the experimental group and the control group at 2:1. Finally, 40 cases in the experimental group and 20 cases in the control group were collected. There was no significant difference in sex, age, weight and illness between the two groups before treatment. The experimental group was treated with traditional Chinese medicine acupoint application combined with oral Chinese medicine ointment, while the control group was treated with simple oral Chinese medicine ointment. Both groups were treated with a course of treatment and followed up for 3 months. After the course of treatment, the improvement of the main symptom, the secondary symptom score and the total score of TCM syndromes were compared between the two groups, and the clinical effect of two different treatment schemes on children asthma in remission period was evaluated. Results: a total of 60 cases were observed, including 40 cases in the treatment group and 20 cases in the control group. The results are as follows: 1. After treatment, the main symptoms of the two groups were improved: the experimental group was significantly better than the control group in terms of wheezing and the frequency of cold attack during the attack; the experimental group was superior to the control group in improving the wheezing during the attack of asthma, and in the nasal obstruction and itching, the treatment group was superior to the control group in improving the asthmatic attack. The curative effect was similar to that of the control group (P 0.05). After treatment, the improvement of secondary symptoms in the two groups: the treatment group and the control group were similar to the control group (P 0.05). Evaluation of curative effect: clinical recovery, remarkable effect, effective and ineffective cases were 816 / 14 / 2 in the experimental group, while in the control group, the clinical recovery, marked effect and effective were 2 / 4 / 10 / 10 / 4, and the clinical recovery rate was 4 / 10 / 4, respectively. The total effective rates were 20.0 and 10.0 in the treatment group and 10.0 and 80.0 in the control group, respectively. The difference was statistically significant (P 0.05), and the experimental group was better than the control group. No side effects were found in the treatment and follow-up in both the trial group and the control group. Conclusion: the Chinese medicine acupoint application combined with traditional Chinese medicine ointment and simple Chinese medicine ointment have good curative effect on children asthma in remission period, the former is better than the latter, and the clinical use safety is good.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R272

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