黑龙江地区儿童目下黑病因的病例对照研究

发布时间：2018-06-18 16:57

本文选题：儿童 + 目下黑　；参考：《黑龙江中医药大学》2017年硕士论文

【摘要】：目的:采用病例对照研究的方法,综合分析黑龙江地区儿童"目下黑"症状形成的原因,帮助临床诊断及早期干预治疗。方法:本研究收集黑龙江中医药大学附属第一医院儿科门诊及病房(2016年03月-2016年12月)年龄在3～14岁儿童240例。分为两组,病例组:有目下黑体征儿童120例,对照组:无目下黑体检儿童120例。通过病例对照的研究方法,采取单因素x2检验及多因素logistic回归分析的方法,分析黑龙江地区儿童目下黑形成的原因。结果:1.经单因素x2检验:经分析肺虚证、脾虚证、血瘀证、上颌窦炎、筛窦炎、腺样体肥大、过敏性鼻炎7项因素在目下黑儿童中发生比例高于对照组,具有统计学意义(P值0.05),肾虚证、额窦炎、蝶窦炎3项因素在目下黑儿童中发生比例与对照组相比差异较小,无统计学意义(P值0.05)。2.经多因素logistic回归分析:单因素分析后筛选出的肺虚证(OR=3.150)、血瘀证(OR=5.366)、上额窦炎(OR=6.005)、腺样体肥大(OR=9.438)、过敏性鼻炎(OR=4.402)5项因素都与目下黑的产生密切相关;脾虚证、筛窦炎2项因素的P值0.05,无统计学意义。结论:1.黑龙江地区儿童目下黑与多种因素相关。2.肺虚证、血瘀证、上额窦炎、腺样体肥大、过敏性鼻炎5项因素为黑龙江地区儿童目下黑的独立危险因素。
[Abstract]:Objective: to analyze the causes of the symptoms of children in Heilongjiang province by case-control study, and to help the clinical diagnosis and early intervention. Methods: 240 pediatric outpatients and wards (from March 2016 to December 2016) in the first affiliated Hospital of Heilongjiang University of traditional Chinese Medicine were collected. The patients were divided into two groups: 120 children with black signs and 120 children without black physical examination. By means of case control, single factor x2 test and multivariate logistic regression analysis were used to analyze the causes of the formation of melanoma in children in Heilongjiang province. The result is 1: 1. Single factor x2 test: the incidence rate of lung deficiency syndrome, spleen deficiency syndrome, blood stasis syndrome, maxillary sinusitis, ethmoiditis, adenoid hypertrophy and allergic rhinitis was higher in black children than that in control group. There was no significant difference in the incidence of P value between the three factors (P value 0.05, kidney deficiency, frontal sinusitis, sphenoid sinusitis) compared with the control group, and there was no significant difference between the three factors. Multivariate logistic regression analysis showed that all the factors selected after univariate analysis were closely related to the formation of blackness, such as lung deficiency syndrome (OR3.150D), blood stasis syndrome (ORN) 5.366N, frontal sinusitis syndrome (OR6.005), adenoid hypertrophy (OR9.438N), allergic rhinitis (OR4.402), and spleen deficiency syndrome (Spleen-deficiency syndrome). The P value of two factors of ethmoiditis was 0.05, which had no statistical significance. Conclusion 1. Children in Heilongjiang area are related to many factors. 2. Lung deficiency syndrome, blood stasis syndrome, upper frontal sinusitis, adenoid hypertrophy and allergic rhinitis were the independent risk factors for children in Heilongjiang province.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R272

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