丹参注射液治疗小儿系膜增生性肾炎的临床观察

发布时间：2018-06-28 22:03

  本文选题：丹参注射液 + 系膜增生性肾炎　； 参考：《中成药》2017年08期

【摘要】：目的观察丹参注射液治疗小儿系膜增生性肾炎(MsPGN)的临床应用效果。方法对102例肾活检确诊的MsPGN患儿的临床资料进行回顾性研究,采用随机数字表法分为观察组和对照组各51例。对照组口服醋酸泼尼松片;观察组给予醋酸泼尼松片的同时静脉滴注丹参注射液。检测各组MsPGN患儿治疗前后的24 h尿蛋白定量(24h TP)、尿红细胞(UM-RBC)数、血清肿瘤坏死因子-α(TNF-α)、Ⅳ型胶原(IV-C)水平的变化,并分析临床疗效。结果与对照组相比,观察组患儿的24h TP、UM-RBC计数及血清TNF-α和IV-C水平均明显下降(P0.05);观察组的总有效率(88.23%),明显高于对照组(76.47%),两组间差异显著(P0.05)。结论在常规西药治疗基础上加用丹参注射液可提高MsPGN患儿的临床疗效。
[Abstract]:Objective to observe the clinical effect of salvia miltiorrhiza injection on Mesangial proliferative glomerulonephritis (MsPGN) in children. Methods the clinical data of 102 children with MsPGN confirmed by renal biopsy were retrospectively studied. The patients were randomly divided into two groups: observation group (n = 51) and control group (n = 51). The control group was given prednisone acetate tablets and the observation group was treated with prednisone acetate tablets and Danshen injection. 24 h urinary protein quantitative (24 h TP), urine red blood cell (UM-RBC), serum tumor necrosis factor- 伪 (TNF- 伪) and type 鈪，

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