郑州市2015年轻、重症手足口病患儿的临床体征、实验室指标动态分析

发布时间：2018-07-01 12:21

本文选题：手足口病 + 实验室指标　；参考：《郑州大学学报(医学版)》2017年05期

【摘要】：目的:探讨轻、重症手足口病患儿实验室指标随时间的动态变化及重症化结局的影响因素。方法:采用问卷调查收集187例手足口病患儿的基本情况和实验室指标,将患儿分为轻症组和重症组,实验室指标分为不同发病时间组,分析轻、重症患儿的实验室指标变化情况及重症化结局影响因素。结果:轻、重症手足口病患儿的中性细胞比率、淋巴细胞比率、Ig M、降钙素原均随时间动态变化(P0.05);中性粒细胞比率(OR=1.198,P=0.001)、淋巴细胞比率(OR=1.194,P=0.002)、白细胞个数(OR=0.916,P=0.024)、血清钠离子(OR=0.690,P0.001)是手足口病患儿重症化结局的影响或预警实验室指标。结论:手足口病患儿病程中免疫水平处于动态变化,且影响重症化结局。
[Abstract]:Objective: to investigate the dynamic changes of laboratory indexes and the factors influencing the outcome of severe hand, foot and mouth disease in children with mild and severe hand, foot and mouth disease. Methods: 187 children with hand, foot and mouth disease were divided into mild and severe group by questionnaire, and the laboratory indexes were divided into different time groups. The changes of laboratory indexes and the influencing factors of severe outcome in severe children. Results: the percentage of neutrophils in children with mild and severe HFMD, The ratio of lymphocytes to Ig M and procalcitonin changed dynamically with time (P0.05), neutrophil ratio (OR1. 198 / P0. 001), lymphocyte ratio (OR1. 194) P0. 002, number of white blood cells (OR0. 916, P0. 024), serum sodium ions (OR0. 690, P0. 001) were the influence of severe outcome of hand, foot and mouth disease or early warning laboratory index. Conclusion: the immune level in children with HFMD is dynamic and affects the outcome of severe disease.
【作者单位】：郑州大学公共卫生学院流行病学教研室;
【基金】：国家自然科学基金81573205
【分类号】：R725.1

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