不同喂养方式对极低出生体质量儿胃肠功能影响的比较

发布时间：2018-07-02 11:27

本文选题：经幽门喂养 + 胃肠营养　；参考：《肠外与肠内营养》2017年04期

【摘要】：目的:探讨经幽门喂养(TP)和经胃管喂养(IG)对极低出生体质量儿胃肠功能的影响,以制订合理的早期肠内营养(EEN)方案。方法:将60例极低出生体质量儿随机分为TP组和IG组,每组各30例。观察两组病儿呼吸暂停发生频率、体质量增长速度、达出生体质量时间、喂养不耐受时间、达TEN时间、宫外发育迟缓(EUGR)发生率以及胃动素、胃泌素、住院时间、喂养相关并发症、坏死性小肠结肠炎和肠穿孔等指标。结果:TP组病儿喂养不耐受时间和达TEN时间均明显低于IG组(P0.05),呼吸暂停发生频率明显低于IG组(P0.01)。两组病儿的体质量增长速度、出院时EUGR发生率、并发症坏死性小肠结肠炎和住院时间均无显著性差异(P0.05)。两组病儿胃动素和胃泌素水平出生后第8天与喂养前比较有显著性差异(P0.01),且胃动素水平TP组明显高于IG组,差异有显著性统计学意义(P0.01)。结论:TP可用于胃管喂养耐受性差或反复出现呼吸暂停的极低出生体质量儿,在进行喂养时应针对不同情况制订个体化方案。
[Abstract]:Objective: to investigate the effects of pyloric feeding (TP) and transgastric tube feeding (IG) on gastrointestinal function in very low birth weight infants in order to establish a reasonable scheme of early enteral nutrition (EEN). Methods: 60 very low birth weight infants were randomly divided into TP group and IG group with 30 cases in each group. The frequency of apnea, growth rate of body mass, time to birth weight, feeding intolerance time, time to TEN, incidence of extrauterine growth retardation (EUGR), motilin, gastrin, hospitalization time were observed. Feeding related complications, necrotizing enterocolitis and intestinal perforation. Results the feeding intolerance time and the time of reaching TEN were significantly lower and the frequency of apnea was significantly lower in the control group than in the IG group (P0.05) and the frequency of apnea was significantly lower than that in the IG group (P0.01). There was no significant difference in the growth rate of body mass, the incidence of EUGR, the complications of necrotizing enterocolitis and hospital stay between the two groups (P0.05). There was significant difference in motilin and gastrin levels between the two groups on the 8th day after birth (P0.01), and the level of motilin in TP group was significantly higher than that in IG group (P0.01). Conclusion\% TP can be used to feed very low birth weight infants with poor tolerance or recurrent apnea in gastric tube feeding. Individualized feeding should be made according to different conditions.
【作者单位】：南京医科大学附属儿童医院新生儿科;
【分类号】：R459.3;R722.6

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