轻度胃肠炎伴婴幼儿良性惊厥的临床分析及随访研究

发布时间：2018-07-07 11:20

本文选题：轻度胃肠炎伴婴幼儿良性惊厥 + 临床特点　；参考：《中国当代儿科杂志》2017年11期

【摘要】：目的分析轻度胃肠炎伴婴幼儿良性惊厥(BICE)的临床特点及预后。方法对436例BICE患儿的临床资料进行回顾性分析,并对其中206例患儿进行1.5~7年的预后随访,邀请部分家长完成Weiss功能缺陷量表以评价患儿远期的社会功能。结果患儿发病年龄多在13~24月龄;发病时间多在9月至次年2月;惊厥主要表现为全身强直-阵挛发作,多在发病24 h内发作,每次持续时间多在5 min内,可有丛集性发作。206例患儿随访过程中,除1例仍有vN样放电,其余脑电图复查均恢复正常,所有患儿家属认为患儿智力正常,无明显性格改变。基于部分BICE患儿家长填写的Weiss功能缺陷量表显示,BICE患儿的远期社会功能与年龄、性别相匹配的健康对照儿童比较差异无统计学意义。结论 BICE多发生于1~2岁婴幼儿,多表现为短暂的全面性发作,部分可表现为丛集性发作,但极少进展为癫vN,预后良好。
[Abstract]:Objective to analyze the clinical features and prognosis of mild gastroenteritis with benign convulsion (Bice) in infants. Methods Clinical data of 436 children with Bice were retrospectively analyzed and 206 of them were followed up for 1.5 ~ 7 years. Some parents were invited to complete the Weiss dysfunction scale to evaluate the long-term social function of the children. Results the age of onset was 13 ~ 24 months, the onset time was from September to February, and the convulsions were mainly generalized tonic-clonic seizures, which occurred within 24 hours and lasted within 5 min. During the follow-up of the patients with cluster seizures, except for one patient who still had vN-like discharge, all the patients returned to normal. All the family members thought that the intelligence of the children was normal, and no significant personality changes were found. Based on the Weiss functional defect scale filled out by some parents of BICE children, there was no significant difference in long-term social function and age, sex matched healthy control children. Conclusion Bice mostly occurs in children aged 1 to 2 years old, most of them are transient comprehensive seizures, some of them are cluster seizures, but very few progress to epileptic vN, and the prognosis is good.
【作者单位】：温州医科大学附属第二医院儿科;
【基金】：温州市公益性科技计划项目(Y20150143)
【分类号】：R720.597

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