小于六个月婴幼儿主动脉缩窄离体球囊扩张效果研究

发布时间：2018-07-11 12:19

本文选题：主动脉缩窄 + 儿童　；参考：《中国循环杂志》2017年02期

【摘要】：目的:观察、评价小于六个月婴幼儿主动脉缩窄离体球囊扩张的可行性。方法:本中心2011-01至2015-12期间,共有13例小于6个月龄主动脉缩窄婴幼儿,男9例,女性4例,年龄20天~6个月(平均3.4个月),体重3.6~6.2 kg(平均4.8 kg)。术中切除主动脉狭窄段,对其采用狭窄段直径2~4倍经皮血管成形术(PTA)外周球囊扩张,计算狭窄段扩张前后直径变化,并进行苏木精-伊红(HE)染色,观察中层平滑肌变化。结果:其中8例合并非限制性室间隔缺损(其中3例行分期手术),2例房间隔缺损,3例主动脉瓣二瓣式,3例动脉导管未闭,1例心包积液。手术过程中留取13例主动脉缩窄患儿的主动脉狭窄段,其中9例为隔膜型,4例为管型狭窄。行球囊扩张后,其直径略有增长,平均增长0.2 mm,未见明显变化,采用HE染色示其内层粘膜脱落,但中层平滑肌连续性完整。结论:球囊扩张治疗小于6个月龄婴幼儿主动脉缩窄效果差,建议采用外科手术治疗此类患儿。
[Abstract]:Objective: to evaluate the feasibility of isolated balloon dilatation of aortic coarctation in infants less than 6 months old. Methods: from January 2011 to December 2015-12, there were 13 infants with aortic coarctation less than 6 months old, 9 males and 4 females, aged from 20 days to 6 months (mean 3.4 months) and weighing 3.6 kg (mean 4.8 kg). Aortic stenosis segment was resected during operation. Percutaneous transluminal angioplasty (PTA) was used to dilate the stenosis segment by percutaneous transluminal angioplasty (PTA). The diameter of stenosis segment before and after dilation was calculated. The changes of medial smooth muscle were observed by hematoxylin eosin (HE) staining. Results: among them, 8 cases were complicated with unrestricted ventricular septal defect (3 cases), 2 cases had atrial septal defect (3 cases), 3 cases had aortic valve double valve type, 3 cases had patent ductus arteriosus, 1 case had pericardial effusion. During the operation, 13 children with coarctation of aorta were treated with aortic stenosis, 9 of them were membranous stenosis, 4 were tubular stenosis. After balloon dilatation, the diameter increased slightly, and the average increase was 0.2 mm. There was no obvious change. He staining showed that the inner mucosa was shedding, but the continuity of the medial smooth muscle was intact. Conclusion: balloon dilatation is not effective for aortic coarctation in infants under 6 months old.
【作者单位】：青岛妇女儿童医院心脏中心;
【基金】：2014年青岛市医疗卫生A类重点学科资助(编号XK2014-001)
【分类号】：R726.5

【相似文献】