加味定喘汤治疗小儿喘息性支气管炎（痰热壅肺证）疗效观察

发布时间：2018-08-03 10:56

【摘要】：目的:观察加味定喘汤治疗小儿喘息性支气管炎痰热壅肺证咳嗽、喘息、喉中痰鸣症状的临床疗效。方法:选择64例小儿喘息性支气管炎(痰热壅肺证)病患儿童,在实际临床研究期间,共脱落病例4例(治疗组脱落2例,依从性差不能接受口服汤剂治疗2例;对照组脱落2例,其中接受其他治疗而剔除1例,失访1例),最终实际完成病例数共60例,将其随机分为治疗组、对照组。治疗组30例患儿予口服加味定喘汤,对照组30例患儿予口服小儿肺热咳喘颗粒,疗程7天。按症状量化积分表对治疗前、后主症、次症及总积分进行评估,用SPSS19.0处理实验数据,比较治疗前、后的症候积分情况、总积分情况、临床疗效。结果:1.治疗1周后,治疗组总有效率为90.0%,对照组总有效率为76.7%,治疗组优于对照组,经数据分析处理比较,P0.05,具有统计学意义。2.两组患儿治疗前、后相比较,在总积分及单项主症积分(咳嗽、喘息、喉中痰鸣)有明显降低,具有统计学意义;经t检验P0.05,具有统计学意义。结论:1、加味定喘汤治疗小儿喘息性支气管炎(痰热壅肺证)有良好的临床疗效。2、加味定喘汤治疗小儿喘息性支气管炎(痰热壅肺证)可以有效缓解或消除患儿咳嗽、喘息、喉中痰鸣临床症状。
[Abstract]:Objective: to observe the clinical effect of Jiawei Dingchuan decoction on cough, wheeze and phlegm in children with asthmatic bronchitis. Methods: 64 children with asthmatic bronchitis (phlegm-heat obstructing lung syndrome) were selected. There were 4 cases of shedding (2 cases of shedding in the treatment group and 2 cases of poor compliance with oral decoction) during the actual clinical study. In the control group, 2 cases were dropped out, among which 1 case was removed by other treatment, and 1 case was lost. Finally, 60 cases were finished. They were randomly divided into the treatment group and the control group. 30 children in the treatment group were treated with Jiawei Dingchuan decoction and 30 children in the control group were treated with the children's Feirekechuan granule for 7 days. According to the symptom quantitative integral table, the main symptom, secondary symptom and total integral were evaluated before and after treatment. The experimental data were processed with SPSS19.0, and the symptom integral, total integral and clinical effect were compared before and after treatment. The result is 1: 1. After one week of treatment, the total effective rate of the treatment group was 90.0g and the total effective rate of the control group was 76.7. the treatment group was superior to the control group (P 0.05). Before and after treatment, the total score and the single main symptom score (cough, wheezing, phlegm in larynx) were significantly decreased in the two groups, and there was statistical significance by t test (P0.05). Conclusion the modified Dingchuan decoction has good clinical efficacy in treating children with asthmatic bronchitis (phlegm-heat obstruction of lung syndrome), and Jiawei Dingchuan decoction can effectively relieve or eliminate cough and wheeze in children with asthmatic bronchitis (phlegm-heat blockage of lung syndrome). Clinical symptoms of phlegm in larynx.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R272

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