酸甘化阴法治疗小儿气阴两虚型腹泻60例临床观察

发布时间：2018-08-12 10:09

【摘要】：目的：小儿腹泻病是儿科临床常见病,本研究基于酸甘化阴理论,结合小儿生理病理特点,通过临床研究,考察酸甘化阴法(加味人参乌梅汤)治疗小儿气阴两虚型腹泻的疗效,为进一步发挥中医药治疗小儿腹泻病优势提供依据,为中药新药的开发奠定基础。方法：选用60例均符合小儿气阴两虚证临床特点的患儿,随机分成治疗组和对照组,治疗组和对照组各30例。治疗组采用以酸甘化阴为法制定的加味人参乌梅汤口服治疗,对照组采用思密达和金双歧口服治疗,经服药6天后,系统的观察两组有效率及两组在减少大便次数、改善大便性状等临床主要症状方面的差别,并同时观察患儿精神、饮食、皮肤弹性、口渴等气阴两虚症状的改善情况,从而判定酸甘化阴法治疗小儿气阴两虚腹泻的临床疗效。结果：本研究的60例患儿中,治疗组显控率73.3%,对照组显控率56.67%,采用酸甘化阴法方药治疗组显控率显著高于口服思密达和金双歧对照组；治疗前,治疗组和对照组患儿症状体征无显著性差异(P0.05),有可比性；治疗后,治疗组症状体征的改善明显优于对照组。结论：酸甘化阴法(加味人参乌梅汤)能有效治疗小儿气阴两虚型腹泻,其证候疗效及对症状的改善,作用优于思密达加金双歧口服。
[Abstract]:Objective: infantile diarrhea is a common disease in pediatrics. Based on the theory of acid-glycosylation of yin and combined with the physiological and pathological characteristics of children, the clinical study was carried out. To investigate the curative effect of sour glycyrrhizic method (modified ginseng wumei decoction) on diarrhea of children with deficiency of both qi and yin, to provide the basis for further exerting the superiority of traditional Chinese medicine in treating diarrhea in children, and to lay a foundation for the development of new drugs of traditional Chinese medicine. Methods: 60 cases of children with deficiency of qi and yin were randomly divided into treatment group and control group, 30 cases in treatment group and 30 cases in control group. The treatment group was treated by oral administration of modified Ginseng Wumei decoction, and the control group was treated by oral administration of smecta and Jin Bifidobacterium. After 6 days of administration, the effective rate of the two groups and the number of defecation in the two groups were observed systematically. At the same time, we observed the improvement of Qi and Yin deficiency symptoms, such as spirit, diet, skin elasticity, thirst and so on, so as to determine the clinical effect of acid-glycosylated yin method in treating children with diarrhea due to deficiency of qi and yin. Results: the control rate of the treatment group was 73.3%, the control rate of the control group was 56.67%. The apparent control rate of the treatment group was significantly higher than that of the oral smecta and Jin Bifidobacterium group, and before treatment, the control rate of the treatment group was significantly higher than that of the control group, and the control rate of the control group was significantly higher than that of the control group. There was no significant difference in symptoms and signs between the treatment group and the control group (P0.05). After treatment, the improvement of symptoms and signs in the treatment group was significantly better than that in the control group. Conclusion: the method of sour glycosylation of Yin (modified Ginseng Wumei decoction) can effectively treat diarrhea of deficiency of Qi and Yin, its syndromes curative effect and the improvement of symptoms, the effect is better than that of smecta plus Jin Bifidobacterium oral.
【学位授予单位】：成都中医药大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R272

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