加减温胆汤治疗痰热互结型小儿肠系膜淋巴结炎的临床疗效观察
发布时间：2018-08-16 13:03
【摘要】：目的:通过中药加减温胆汤治疗小儿肠系膜淋巴结炎的临床疗效观察,比较治疗组和对照组患儿治疗前后证候总积分,淋巴结大小及治疗后总有效,探讨中医药治疗小儿肠系膜淋巴结炎的有效方法。方法:将66例小儿肠系膜淋巴结炎患儿随机分为对照组和治疗组,各33例,治疗组予以中药加减温胆汤颗粒剂口服2周,对照组予以头孢丙烯颗粒口服1周,而后改为酪酸梭菌活菌片继续服用1周。两组患儿在2周疗程结束后进行临床疗效和中医证候总积分的比较,同时复查腹腔彩超,随访复发率。结果:(1)两组总疗效比较:治疗组总有效率为90.9%,对照组总有效率为66.7%,两组差异具有统计学意义(P㩳0.05)。(2)治疗组和对照组均可改善治疗前后中医证候总积分,两组治疗前后具有统计学意义(P㩳0.05);两组治疗后差异具有显著统计学意义(P㩳0.05),故治疗组疗效明显优于对照组。(3)两组患儿治疗后主要症状体征改善比较:两组差异具有统计学意义(P㩳0.05)。(4)两组患儿治疗后次要症状体征的消失率比较:咽红情况、腹胀情况、恶心呕吐、大小便方面两组差异具有统计学意义(P㩳0.05);脉象方面两组差异无统计学意义(P㧐0.05)。(5)两组患儿腹痛改善情况比较:治疗组3天和7天腹痛改善情况差异具有统计学意义(P㩳0.05);对照组3天和7天时腹痛改善情况差异无统计学意义(P㧐0.05)。(6)两组患儿腹部彩色多普勒改善情况比较:两组治疗对淋巴结横径和纵径均有改善,差异具有统计学意义(P㩳0.05);治疗组和对照组治疗后横径和纵径差异具有统计学意义(P㩳0.05)。(7)两组患儿腹痛复发率比较:两组复发率差异无统计学意义(P㧐0.05)。结论:(1)治疗组总疗效明显优于对照组,说明加减温胆汤治疗小儿肠系膜淋巴结炎具有显著优势。(2)治疗组在降低中医证候总积分、改善主要症状体征及次要症状消失率明显优于对照组。(3)治疗组在改善腹痛情况方面,第7天时腹痛改善情况明显优于对照组。(4)两组患儿腹部彩色多普勒改善情况比较:两组患儿在治疗后淋巴结横径和纵径均较治疗前改善,但治疗组在淋巴结横径和纵径方面改善均明显优于对照组。(5)两组患儿腹痛复发率比较:在治疗后随访的2月中,治疗组和对照组的复发率经过统计学分析,差异无统计学意义,即治疗组在复发率方面无明显优势。
[Abstract]:Objective: to observe the clinical effect of traditional Chinese medicine plus Jiangwangtang in treating mesenteric lymphadenitis in children, and to compare the total syndromes integral, lymph node size and total effect after treatment between the treatment group and the control group. To explore the effective method of treating mesenteric lymphadenitis in children with traditional Chinese medicine. Methods: 66 children with mesenteric lymphadenitis were randomly divided into control group (n = 33) and treatment group (n = 33). And then changed to Clostridium caseate live bacteria tablets continue to take for 1 week. The clinical efficacy and the total score of TCM syndromes were compared between the two groups after 2 weeks of treatment. Results: (1) comparison of the total curative effect between the two groups: the total effective rate in the treatment group was 90.9 and the total effective rate in the control group was 66.7. The difference between the two groups was statistically significant (P0. 05). (2) both the treatment group and the control group could improve the total score of TCM syndromes before and after treatment. There was significant difference between the two groups before and after treatment (P0. 05), so the curative effect of the treatment group was obviously better than that of the control group. (3) the main symptoms and signs of the two groups were improved after treatment: the difference between the two groups was uniform. Comparison of the disappearance rate of secondary symptoms and signs between the two groups after treatment: pharynx red condition. Abdominal distension, nausea and vomiting, There were significant differences between the two groups (P0. 05), but there was no significant difference in pulse (P0. 05). (5) between the two groups: the improvement of abdominal pain in the treatment group was statistically significant at 3 days and 7 days (P0. 05), and there was no significant difference between the two groups in the improvement of abdominal pain (P0. 05). There was no significant difference in the improvement of abdominal pain between the two groups at day 3 and day 7 (P0. 05). (6). There was no significant difference in the improvement of abdominal color Doppler between the two groups: the transverse diameter and longitudinal diameter of lymph nodes were improved in both groups. The difference was statistically significant (P0. 05), and the difference of transverse and longitudinal diameter between the treatment group and the control group was statistically significant (P0. 05). (7). There was no significant difference in the recurrence rate of abdominal pain between the two groups (P0. 05). Conclusion: (1) the total curative effect of the treatment group is significantly better than that of the control group, which indicates that the treatment group has significant advantages in treating children with mesenteric lymphadenitis. (2) the treatment group is reducing the total integral of TCM syndromes. The improvement of main symptoms and signs and the disappearance rate of secondary symptoms were significantly better than that of the control group. (3) in the treatment group, the abdominal pain was improved, On the 7th day, the improvement of abdominal pain was better than that of the control group. (4) the improvement of abdominal color Doppler: after treatment, the transverse diameter and longitudinal diameter of lymph nodes in the two groups were improved compared with those before treatment. But the improvement of the transverse and longitudinal diameter of lymph nodes in the treatment group was significantly better than that in the control group. (5) the recurrence rate of abdominal pain in the two groups was compared: the recurrence rate of abdominal pain in the treatment group and the control group was statistically analyzed in 2 months after treatment, and there was no significant difference between the treatment group and the control group. That is, the treatment group in the recurrence rate has no obvious advantage.
【学位授予单位】：安徽中医药大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R272
本文编号：2186064
[Abstract]:Objective: to observe the clinical effect of traditional Chinese medicine plus Jiangwangtang in treating mesenteric lymphadenitis in children, and to compare the total syndromes integral, lymph node size and total effect after treatment between the treatment group and the control group. To explore the effective method of treating mesenteric lymphadenitis in children with traditional Chinese medicine. Methods: 66 children with mesenteric lymphadenitis were randomly divided into control group (n = 33) and treatment group (n = 33). And then changed to Clostridium caseate live bacteria tablets continue to take for 1 week. The clinical efficacy and the total score of TCM syndromes were compared between the two groups after 2 weeks of treatment. Results: (1) comparison of the total curative effect between the two groups: the total effective rate in the treatment group was 90.9 and the total effective rate in the control group was 66.7. The difference between the two groups was statistically significant (P0. 05). (2) both the treatment group and the control group could improve the total score of TCM syndromes before and after treatment. There was significant difference between the two groups before and after treatment (P0. 05), so the curative effect of the treatment group was obviously better than that of the control group. (3) the main symptoms and signs of the two groups were improved after treatment: the difference between the two groups was uniform. Comparison of the disappearance rate of secondary symptoms and signs between the two groups after treatment: pharynx red condition. Abdominal distension, nausea and vomiting, There were significant differences between the two groups (P0. 05), but there was no significant difference in pulse (P0. 05). (5) between the two groups: the improvement of abdominal pain in the treatment group was statistically significant at 3 days and 7 days (P0. 05), and there was no significant difference between the two groups in the improvement of abdominal pain (P0. 05). There was no significant difference in the improvement of abdominal pain between the two groups at day 3 and day 7 (P0. 05). (6). There was no significant difference in the improvement of abdominal color Doppler between the two groups: the transverse diameter and longitudinal diameter of lymph nodes were improved in both groups. The difference was statistically significant (P0. 05), and the difference of transverse and longitudinal diameter between the treatment group and the control group was statistically significant (P0. 05). (7). There was no significant difference in the recurrence rate of abdominal pain between the two groups (P0. 05). Conclusion: (1) the total curative effect of the treatment group is significantly better than that of the control group, which indicates that the treatment group has significant advantages in treating children with mesenteric lymphadenitis. (2) the treatment group is reducing the total integral of TCM syndromes. The improvement of main symptoms and signs and the disappearance rate of secondary symptoms were significantly better than that of the control group. (3) in the treatment group, the abdominal pain was improved, On the 7th day, the improvement of abdominal pain was better than that of the control group. (4) the improvement of abdominal color Doppler: after treatment, the transverse diameter and longitudinal diameter of lymph nodes in the two groups were improved compared with those before treatment. But the improvement of the transverse and longitudinal diameter of lymph nodes in the treatment group was significantly better than that in the control group. (5) the recurrence rate of abdominal pain in the two groups was compared: the recurrence rate of abdominal pain in the treatment group and the control group was statistically analyzed in 2 months after treatment, and there was no significant difference between the treatment group and the control group. That is, the treatment group in the recurrence rate has no obvious advantage.
【学位授予单位】：安徽中医药大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R272
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