宣肺调脾饮治疗儿童上气道咳嗽综合征（肺脾不调型）临床观察

发布时间：2018-08-18 10:45

【摘要】：目的:观察宣肺调脾饮治疗儿童上气道咳嗽综合征(肺脾不调型)的临床疗效,客观评价其有效性。方法:选择符合西医诊断标准和中医证候标准的上气道咳嗽综合征(肺脾不调型)患儿60例,随机分为治疗组30例,对照组30例。对照组给予布地奈德鼻喷雾剂治疗,治疗组给予宣肺调脾饮治疗,两组均治疗2周评价疗效。治疗开始前与结束后,分别记录咳嗽症状积分、中医证候积分和莱斯特咳嗽问卷积分,通过对比两组咳嗽消失率、主症积分、中医证候疗效及莱斯特咳嗽问卷积分,客观评价宣肺调脾饮的临床疗效。结果:1.咳嗽消失率比较:治疗组30例患儿中,临床控制10例,显效7例,有效11例,无效2例,总有效率93.3%;对照组30例患儿中,临床控制6例,显效12例,有效5例,无效7例,总有效率76.7%。两组总有效率比较,经统计学分析,差异无统计学意义(P0.05),提示两组在咳嗽消失率方面疗效相当。2.主症积分及中医证候疗效比较:(1)两组组内治疗前后主症比较,积分明显降低,差异有统计学意义(P0.05);(2)两组治疗后组见主症积分比较,除“咳嗽”一项积分差异无统计学意义(P0.05),其余主症积分差异均有统计学意义(P0.05)。(3)两组治疗后中医证候疗效比较:治疗组总有效率96.7%,对照组总有效率73.3%,差异有显著统计学意义(P0.01)。3.莱斯特咳嗽问卷积分:(1)两组治疗后莱斯特咳嗽问卷积分较治疗前均有明显改善,统计学有显著性差异(P0.01);(2)治疗组治疗后莱斯特咳嗽问卷积分改善值与对照组比较,差异有显著统计学意义(P0.01)。结论:宣肺调脾饮治疗肺脾不调型儿童上气道咳嗽综合征,疗效确切,能明显改善患儿局部症状和体征,其对患儿咳嗽的改善与布地奈德鼻喷雾剂相当,中医证候疗效优于布地奈德鼻喷雾剂。
[Abstract]:Objective: to observe the clinical effect of Xuanfei Tiaopi decoction (XFTiao Yin) in treating children's upper airway cough syndrome. Methods: sixty children with upper airway cough syndrome (lung and spleen disorder) were randomly divided into treatment group (n = 30) and control group (n = 30). The control group was treated with budesonide nasal spray, the treatment group was treated with Xuanfei Tiaopi decoction, and the two groups were treated with budesonide nasal spray for 2 weeks. Before and after the treatment, cough symptom score, TCM syndrome score and Leicester cough questionnaire score were recorded, respectively. The cough disappearance rate, the main symptom score, the curative effect of TCM syndrome and the Lester cough questionnaire score were compared between the two groups. Objective to evaluate the clinical effect of Xuanfei Tiaopi decoction. The result is 1: 1. There were 10 cases of clinical control, 7 cases of marked effect, 11 cases of effective, 2 cases of ineffective, and 93.3% of total effective rate in the treatment group, while in the control group, there were 6 cases of clinical control, 12 cases of remarkable effect, 5 cases of effective and 7 cases of failure. The total effective rate is 76. 7%. The total effective rate of the two groups was compared by statistical analysis, the difference was not statistically significant (P0.05), suggesting that the two groups in cough disappearance rate is equivalent. 2. 2. Main symptom score and TCM syndrome efficacy comparison: (1) the main symptoms of the two groups before and after treatment, the score significantly decreased, the difference was statistically significant (P0.05); (2) after treatment in the two groups to see the main symptom score comparison, Except "cough" one integral difference has no statistical significance (P0.05), the other main symptom integral difference all has the statistical significance (P0.05). (3) two groups after the treatment traditional Chinese medicine syndrome curative effect comparison: the treatment group total effective rate 96.7%, the control group total effective rate 73.3%, the difference has the statistical significance (P0.01) .3. The score of Leicester cough questionnaire: (1) after treatment, the score of Leicester cough questionnaire in the two groups was significantly improved compared with that before treatment (P0.01); (2). The improvement value of Leicester cough questionnaire score in the treatment group was higher than that in the control group after treatment (P0.01); (2). The difference was statistically significant (P0.01). Conclusion: Xuanfei Tiaopi decoction is effective in treating upper airway cough syndrome of children with lung and spleen disorder, and can obviously improve the local symptoms and signs of children. The improvement of cough in children is similar to that of budesonide nasal spray. The curative effect of TCM syndrome is better than budesonide nasal spray.
【学位授予单位】：山西医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R272

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