新生儿胃肠穿孔80例临床特点及预后分析
发布时间：2018-08-24 19:53
【摘要】：目的分析新生儿胃肠穿孔的病因、临床特征、治疗及预后。方法回顾性分析2004年1月至2015年12月复旦大学附属儿科医院新生儿科收治的80例新生儿胃肠穿孔患儿的临床资料,根据出生胎龄分为早产儿组与足月儿组,比较两组间的病因、临床表现、治疗及预后。结果 80例新生儿胃肠穿孔中,早产儿62例,足月儿18例。两组病因均以坏死性小肠结肠炎(necrotizing enterocolitis,NEC)为主,临床均以腹胀为主要表现,早产儿发生反应差、休克、弥散性血管内凝血明显多于足月儿(P0.05)。早产儿组平均发病日龄9(1.75,20)d,足月儿组平均发病日龄4.5(1,7.75)d。62例手术治疗,其中胃穿孔8例,肠穿孔54例,18例因未手术穿孔部位不明确。死亡32例,病死率40%,早产儿死亡26例(病死率41.9%),足月儿死亡6例(病死率33.3%)。结论新生儿胃肠穿孔是新生儿期的严重疾病,病死率高。早期诊断、积极治疗和尽早外科干预可能提高患儿的存活率,显著改善患儿的预后。
[Abstract]:Objective to analyze the etiology, clinical features, treatment and prognosis of neonatal gastrointestinal perforation. Methods the clinical data of 80 newborns with gastrointestinal perforation were analyzed retrospectively from January 2004 to December 2015 in the Department of Neonatrics, affiliated Pediatrics Hospital of Fudan University. According to the gestational age, they were divided into premature group and term group. The etiology of the two groups was compared. Clinical manifestation, treatment and prognosis. Results among 80 cases of neonatal gastrointestinal perforation, 62 cases were premature and 18 cases were full-term. The main etiology of the two groups was necrotizing enterocolitis (necrotizing enterocolitis,NEC). Abdominal distension was the main clinical manifestation. Premature infants had poor response shock and disseminated intravascular coagulation were significantly more than full-term infants (P0.05). The average onset age of premature infants was 9 (1.75 ~ 20) days, and that of term infants was 4.5 (1 / 7.75) d.62. There were 8 cases of gastric perforation and 54 cases of intestinal perforation. There were 32 cases of death, 40 cases of death rate, 26 cases of premature infant death (41.9%) and 6 cases of term infant death (33.3%). Conclusion Neonatal gastrointestinal perforation is a serious disease in neonatal stage with high mortality. Early diagnosis, active treatment and early surgical intervention may improve the survival rate and prognosis of children.
【作者单位】： 复旦大学附属儿科医院新生儿科;
【分类号】：R722.1
本文编号：2201858
[Abstract]:Objective to analyze the etiology, clinical features, treatment and prognosis of neonatal gastrointestinal perforation. Methods the clinical data of 80 newborns with gastrointestinal perforation were analyzed retrospectively from January 2004 to December 2015 in the Department of Neonatrics, affiliated Pediatrics Hospital of Fudan University. According to the gestational age, they were divided into premature group and term group. The etiology of the two groups was compared. Clinical manifestation, treatment and prognosis. Results among 80 cases of neonatal gastrointestinal perforation, 62 cases were premature and 18 cases were full-term. The main etiology of the two groups was necrotizing enterocolitis (necrotizing enterocolitis,NEC). Abdominal distension was the main clinical manifestation. Premature infants had poor response shock and disseminated intravascular coagulation were significantly more than full-term infants (P0.05). The average onset age of premature infants was 9 (1.75 ~ 20) days, and that of term infants was 4.5 (1 / 7.75) d.62. There were 8 cases of gastric perforation and 54 cases of intestinal perforation. There were 32 cases of death, 40 cases of death rate, 26 cases of premature infant death (41.9%) and 6 cases of term infant death (33.3%). Conclusion Neonatal gastrointestinal perforation is a serious disease in neonatal stage with high mortality. Early diagnosis, active treatment and early surgical intervention may improve the survival rate and prognosis of children.
【作者单位】： 复旦大学附属儿科医院新生儿科;
【分类号】：R722.1
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