右美托咪定与舒芬太尼鼻内给药用于儿童口腔科门诊手术镇静的临床观察
发布时间：2018-09-12 14:13
【摘要】：【目的】观察右美托咪定与的舒芬太尼鼻内给药用于儿童门诊手术的镇静效果。【方法】拟行口腔科门诊手术的患儿60例,年龄3~7岁,体质量10~32 kg,性别不限,ASA分级Ⅰ-Ⅱ级。采用随机数字表法,将患儿分为3组(n=20),右美托咪定联合舒芬太尼组(DS组),右美托咪定组(D组)和舒芬太尼组(S组),于术前准备室内分别经鼻予以右美托咪定2μg/kg和舒芬太尼1μg/kg;右美托咪定2μg/kg;舒芬太尼1μg/kg。记录入室时、术中、出室时和PACU中的俄亥俄州大学行为级别评分(OSUBRS)、密歇根州大学镇静评分(UMSS)。记录患儿用药前后的收缩压、心率和用药后不良反应。【结果】入室时和术中的OSUBRS评分DS组低于D组和S组(P0.01);UMSS均高于D组和S组(P0.05)。DS组的镇静成功率高于D组和S组(P0.01)。DS组与D组用药后收缩压和心率下降的百分数无统计学差异(P0.05)。没有患儿发生呼吸抑制、低血压和心动过缓。【结论】右美托咪定与舒芬太尼鼻内给药可为儿童口腔科门诊手术提供满意的镇静,并不伴有呼吸抑制、心动过缓和低血压的不良反应。
[Abstract]:[objective] to observe the sedation effect of dexmetoimidine and sufentanil for pediatric outpatient surgery. [methods] A total of 60 children, aged 37 years, with a body mass of 1032 kg, were enrolled in pediatric outpatient surgery. Using random digital tables, The children were divided into 3 groups: dexmetomidine combined with sufentanil (DS group), dexmetomidine group (D group) and sufentanil group (S group). The patients were given 2 渭 g/kg and 1 渭 g / kg sufentanil, 2 渭 g / kg, 2 渭 g / kg, 1 渭 g / kg, respectively. Record entry time, intraoperative, intraventricular and PACU behavioral grade scores at the University of Ohio, (OSUBRS), University of Michigan sedation score (UMSS). Systolic blood pressure was recorded before and after medication. Heart rate and adverse reaction after medication. [results] the OSUBRS scores of group DS at room entry and during operation were lower than those of group D and group S (P0.01). The sedation success rate of group DS was higher than that of group D and group S (P0.05). The success rate of sedation in group DS was higher than that in group D and group S (P0.01). There was no statistical difference in the percentage of heart rate decrease (P0.05). No children developed respiratory depression, hypotension and bradycardia. [conclusion] Intranasal administration of dexmetomidine and sufentanil can provide satisfactory sedation for pediatric stomatological outpatient surgery without respiratory inhibition. Adverse effects of palliative hypotension.
【作者单位】： 武警后勤学院附属医院麻醉科;
【基金】：武警后勤学院附属医院面上项目(FYM201550)
【分类号】：R726.1
本文编号：2239273
[Abstract]:[objective] to observe the sedation effect of dexmetoimidine and sufentanil for pediatric outpatient surgery. [methods] A total of 60 children, aged 37 years, with a body mass of 1032 kg, were enrolled in pediatric outpatient surgery. Using random digital tables, The children were divided into 3 groups: dexmetomidine combined with sufentanil (DS group), dexmetomidine group (D group) and sufentanil group (S group). The patients were given 2 渭 g/kg and 1 渭 g / kg sufentanil, 2 渭 g / kg, 2 渭 g / kg, 1 渭 g / kg, respectively. Record entry time, intraoperative, intraventricular and PACU behavioral grade scores at the University of Ohio, (OSUBRS), University of Michigan sedation score (UMSS). Systolic blood pressure was recorded before and after medication. Heart rate and adverse reaction after medication. [results] the OSUBRS scores of group DS at room entry and during operation were lower than those of group D and group S (P0.01). The sedation success rate of group DS was higher than that of group D and group S (P0.05). The success rate of sedation in group DS was higher than that in group D and group S (P0.01). There was no statistical difference in the percentage of heart rate decrease (P0.05). No children developed respiratory depression, hypotension and bradycardia. [conclusion] Intranasal administration of dexmetomidine and sufentanil can provide satisfactory sedation for pediatric stomatological outpatient surgery without respiratory inhibition. Adverse effects of palliative hypotension.
【作者单位】： 武警后勤学院附属医院麻醉科;
【基金】：武警后勤学院附属医院面上项目(FYM201550)
【分类号】：R726.1
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