重症联合免疫缺陷病新生儿T淋巴细胞受体切割环筛查概况
发布时间：2018-10-10 10:00
【摘要】：正重症联合免疫缺陷病(severe combined immunodeficiency,SCID)是一组细胞免疫缺陷、同时累及体液免疫的原发性免疫缺陷病(primary immunodeficiency,PID),根据有无B淋巴细胞,可将SCID分为T-B+及T-B-两大类~([1])。随着近期对SCID研究的逐步深入,根据患者外周血T淋巴细胞的绝对计数、T淋巴细胞增殖分化功能及致病基因的类型,将SCID划分为3大类:经典的SCID、泄漏型SCID(leaky
[Abstract]:Positive severe combined immunodeficiency disease (severe combined immunodeficiency,SCID) is a group of primary immunodeficiency disease (primary immunodeficiency,PID), which involves both cellular and humoral immunity. According to the presence of B lymphocytes, SCID can be divided into two categories: T-B and T-B-. With the recent progress in the study of SCID, according to the absolute count of T lymphocytes in peripheral blood of patients, the proliferation and differentiation function of T lymphocytes and the types of pathogenic genes, SCID is divided into three categories: classic SCID, leakage type SCID (leaky.
【作者单位】： 复旦大学附属儿科医院;
【分类号】：R722.1
本文编号：2261351
[Abstract]:Positive severe combined immunodeficiency disease (severe combined immunodeficiency,SCID) is a group of primary immunodeficiency disease (primary immunodeficiency,PID), which involves both cellular and humoral immunity. According to the presence of B lymphocytes, SCID can be divided into two categories: T-B and T-B-. With the recent progress in the study of SCID, according to the absolute count of T lymphocytes in peripheral blood of patients, the proliferation and differentiation function of T lymphocytes and the types of pathogenic genes, SCID is divided into three categories: classic SCID, leakage type SCID (leaky.
【作者单位】： 复旦大学附属儿科医院;
【分类号】：R722.1
【相似文献】
相关期刊论文 前1条
1 洪锦心,米伟民,张华忠,余新生;人类T淋巴细胞受体(TCR)γ基因簇在染色体7P_1区带的新的非随机性异常[J];肿瘤;1988年05期
，本文编号：2261351
本文链接：https://www.wllwen.com/yixuelunwen/eklw/2261351.html
最近更新
教材专著
