新生儿肺透明膜病危险因素分析

发布时间：2018-10-11 19:56

【摘要】：目的对新生儿肺透明膜病(HMD)的危险因素进行分析,为新生儿HMD的防治提供理论依据。方法研究对象选择温州医科大学附属第一医院2015年12月—2016年12月期间收治的80例新生儿HMD患儿以及同时期未患HMD的正常新生儿80例,分别设为观察组与对照组。通过临床检查以及妊娠期检查资料回顾性分析研究HMD的危险因素,并采用Logistic回归分析进行多因素分析,分析HMD的独立危险因素。结果 HMD的危险因素有为胎盘早剥[OR=8.564,95%CI(6.431,39.542)]、母亲糖尿病[OR=9.431,95%CI(4.153,36.431)]、宫内窘迫[OR=11.332,95%CI(1.123,38.457)]、多胎妊娠[OR=7.441,95%CI(2.546,33.431)]、前置胎盘[OR=10.431,95%CI(6.132,23.323)]。结论新生儿HMD的危险因素包括胎盘早剥、母亲糖尿病、宫内窘迫、多胎妊娠、前置胎盘,预防HMD需要加强分娩监护以及高危妊娠的干预治疗,积极预防相关危险因素,降低HMD发生率及死亡率。
[Abstract]:Objective to analyze the risk factors of neonatal hyaline membrane disease (HMD) in order to provide theoretical basis for the prevention and treatment of neonatal HMD. Methods 80 neonates with HMD and 80 normal neonates without HMD were selected from the first affiliated Hospital of Wenzhou Medical University from December 2015 to December 2016. They were divided into two groups: observation group and control group. The risk factors of HMD were analyzed retrospectively by clinical examination and pregnancy examination, and the independent risk factors of HMD were analyzed by Logistic regression analysis. Results the risk factors of HMD were placental abruption [OR=8.564,95%CI (6.431n 39.542)], maternal diabetes mellitus (OR=9.431,95%CI (4.153n 36.431)], intrauterine distress (OR=11.332,95%CI (1.123n 38.457), multiple pregnancy (OR=7.441,95%CI (2.546v 33.431), placenta previa (OR=10.431,95%CI (6.132n 23.323). Conclusion the risk factors of neonatal HMD include placental abruption, maternal diabetes mellitus, intrauterine distress, multiple pregnancy and placenta previa. To prevent HMD, we should strengthen the monitoring of delivery and the intervention treatment of high-risk pregnancy, and actively prevent the related risk factors. The incidence and mortality of HMD were reduced.
【作者单位】：温州医科大学附属第一医院;
【分类号】：R722.1

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