健康教育联合口服补液盐治疗儿童直立性低血压的疗效评价
发布时间：2018-10-26 21:03
【摘要】：目的研究健康教育联合口服补液盐治疗儿童直立性低血压(OH)的疗效以及对直立倾斜试验(HUTT)结果的影响。 方法对2009年-10月～2012年-01月在中南大学湘雅二医院儿童晕厥专科门诊就诊或住院的行HUTT诊断为OH儿童51例,男30例,女21例,年龄4～16岁(平均9.82±2.96岁)。给予健康教育及口服补液盐(ORS)治疗,治疗30d后11例复查HUTT.采用SPSS16.0软件进行统计学分析,使用t检验。 结果30d后OH儿童回院复查11例,其余儿童经电话联系不能坚持治疗方案或不能按时复诊而剔除统计。11例复查HUTT显示：①SBP0(平卧位时收缩压)比较：治疗前与治疗后比较差异无统计学意义(106.27±10.82mmHg vs103.27±8.91mmHg,t=0.710,P0.05)。②SBP3min(站立位3min时收缩压)比较：治疗后比治疗前升高(104.91±9.92mmHg vs90.55±18.06mmHg,t=-2.311,P0.05)。③DBP0(平卧位时舒张压)比较：治疗前后比较差异无统计学意义(70.45±8.89mmHg vs67.27±11.79mmHg,t=0.715,P0.05).④DBP3min(站立位3min时舒张压)比较：治疗后较治疗前升高(70.00±6.15mmHg vs55.18±12.77mmHg,t=-3.469,P0.05).⑤△SBP=SBPO-SBP3min(HUTT3min收缩压下降值)比较：治疗后SBP下降幅度较治疗前明显减小(-1.64±6.23mmHg vs15.73±15.10mmHg,t=3.525,P0.05).⑥△DBP=DBPO-DBP3min(HUTT3min舒张压下降值)比较：治疗后DBP下降幅度较治疗前明显减小(-2.73±11.10mmHg vs15.27±11.24mmHg,t=3.778,P0.05).⑦HRO(HUTT开始前平卧位时心率)比较：治疗前后HR比较无统计学差异(84.73±14.46次/min vs85.73±9.65次/min,t=-0.191,P0.05)；HR3min(HUTT开始后3min时心率)比较：治疗前后HR3min比较差异无统计学意义(94.27±15.96次/min vs105.18±6.69次/min,t=-2.090,P0.05)。⑧不同性别治疗前SBP0、SBP3min、DBP0、DBP3min、HR0、HR3min、△SBP以及△DBP比较：两者比较均无统计学差异(P0.05)；⑨不同性别治疗后SBP0、SBP3min、DBP0、DBP3min、HR0、HR3min、ASBP以及ADBP比较：△SBP男性下降幅度较女性下降小(-6.00±2.24mmHg vs2.00±6.23mmHg,t=-2.709,P0.05)；而SBP0、SBP3min、DBP0、DBP3min、HR0、HR3min、△DBP男性与女性比较差异均无统计学意义。 结论健康教育联合口服补液盐治疗儿童OH近期疗效明显,可改善直立不耐受症状。
[Abstract]:Objective to study the efficacy of health education combined with oral rehydration salt in the treatment of orthostatic hypotension (OH) in children and its effect on the results of vertical tilt test (HUTT). Methods 51 children (30 males and 21 females, mean 9.82 卤2.96 years) with OH were diagnosed by HUTT from 2009 to October to January 2012 in Xiangya second Hospital of Central South University. Health education and oral rehydration salt (ORS) were given to 11 patients with HUTT. after 30 days of treatment. SPSS16.0 software was used for statistical analysis and t test was used. Results after 30 days, 11 children with OH returned to hospital. The other children could not adhere to the treatment plan by telephone or were not able to return on time and the statistics were excluded. HUTT examination of 11 cases showed that 1SBP0 (supine position systolic blood pressure) comparison: there was no significant difference between before and after treatment (P < 0.05). 106.27 卤10.82mmHg vs103.27 卤8.91 mmHg, Comparison of 2SBP3min (systolic blood pressure in standing position 3min): after treatment, it was increased (104.91 卤9.92mmHg vs90.55 卤18.06 mm), (P0.05). Comparison of 3DBP0 (diastolic blood pressure in supine position): there was no significant difference before and after treatment (70.45 卤11.79mm Hgt), and there was no significant difference between the two groups before and after treatment (70.45 卤11.79mm). (P 0.05). Comparison of 4DBP3min (diastolic blood pressure during standing 3min): after treatment, it increased (70.00 卤6.15mmHg vs55.18 卤12.77mm). Comparison of 5 SBP=SBPO-SBP3min (HUTT3min systolic blood pressure decrease): the decrease of SBP after treatment was significantly lower than that before treatment (-1.64 卤6.23mmHg vs15.73 卤15.10 mm SBP 3.525, P < 0.05). Comparison of 6 DBP=DBPO-DBP3min (HUTT3min diastolic blood pressure decrease): the decrease of DBP after treatment was significantly lower than that before treatment (-2.73 卤11.10mmHg vs15.27 卤11.24 mm DBP 3.778, P < 0.05). (P0.05). 7HRO (heart rate before HUTT began to lie down): there was no significant difference in HR before and after treatment (84.73 卤14.46 / min vs85.73 卤9.65 / min,t=-0.191,P0.05); Comparison of HR3min (heart rate at 3min after HUTT): there was no significant difference in HR3min before and after treatment (94.27 卤15.96 / min vs105.18 卤6.69 / min,t=-2.090,P0.05). 8 SBP0,SBP3min,DBP0,DBP3min,HR0, before and after treatment HR3min, SBP and DBP comparison: there was no statistical difference between them (P0.05). 9 comparison of SBP0,SBP3min,DBP0,DBP3min,HR0,HR3min,ASBP and ADBP after different sex treatment: the decrease of SBP in male was smaller than that in female (-6.00 卤2.24mmHg vs2.00 卤6.23mm). There was no significant difference in SBP0,SBP3min,DBP0,DBP3min,HR0,HR3min, DBP between male and female. Conclusion Health education combined with oral rehydration salt can improve the symptoms of orthostatic intolerance in children with OH.
【学位授予单位】：中南大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R725.4
本文编号：2296933
[Abstract]:Objective to study the efficacy of health education combined with oral rehydration salt in the treatment of orthostatic hypotension (OH) in children and its effect on the results of vertical tilt test (HUTT). Methods 51 children (30 males and 21 females, mean 9.82 卤2.96 years) with OH were diagnosed by HUTT from 2009 to October to January 2012 in Xiangya second Hospital of Central South University. Health education and oral rehydration salt (ORS) were given to 11 patients with HUTT. after 30 days of treatment. SPSS16.0 software was used for statistical analysis and t test was used. Results after 30 days, 11 children with OH returned to hospital. The other children could not adhere to the treatment plan by telephone or were not able to return on time and the statistics were excluded. HUTT examination of 11 cases showed that 1SBP0 (supine position systolic blood pressure) comparison: there was no significant difference between before and after treatment (P < 0.05). 106.27 卤10.82mmHg vs103.27 卤8.91 mmHg, Comparison of 2SBP3min (systolic blood pressure in standing position 3min): after treatment, it was increased (104.91 卤9.92mmHg vs90.55 卤18.06 mm), (P0.05). Comparison of 3DBP0 (diastolic blood pressure in supine position): there was no significant difference before and after treatment (70.45 卤11.79mm Hgt), and there was no significant difference between the two groups before and after treatment (70.45 卤11.79mm). (P 0.05). Comparison of 4DBP3min (diastolic blood pressure during standing 3min): after treatment, it increased (70.00 卤6.15mmHg vs55.18 卤12.77mm). Comparison of 5 SBP=SBPO-SBP3min (HUTT3min systolic blood pressure decrease): the decrease of SBP after treatment was significantly lower than that before treatment (-1.64 卤6.23mmHg vs15.73 卤15.10 mm SBP 3.525, P < 0.05). Comparison of 6 DBP=DBPO-DBP3min (HUTT3min diastolic blood pressure decrease): the decrease of DBP after treatment was significantly lower than that before treatment (-2.73 卤11.10mmHg vs15.27 卤11.24 mm DBP 3.778, P < 0.05). (P0.05). 7HRO (heart rate before HUTT began to lie down): there was no significant difference in HR before and after treatment (84.73 卤14.46 / min vs85.73 卤9.65 / min,t=-0.191,P0.05); Comparison of HR3min (heart rate at 3min after HUTT): there was no significant difference in HR3min before and after treatment (94.27 卤15.96 / min vs105.18 卤6.69 / min,t=-2.090,P0.05). 8 SBP0,SBP3min,DBP0,DBP3min,HR0, before and after treatment HR3min, SBP and DBP comparison: there was no statistical difference between them (P0.05). 9 comparison of SBP0,SBP3min,DBP0,DBP3min,HR0,HR3min,ASBP and ADBP after different sex treatment: the decrease of SBP in male was smaller than that in female (-6.00 卤2.24mmHg vs2.00 卤6.23mm). There was no significant difference in SBP0,SBP3min,DBP0,DBP3min,HR0,HR3min, DBP between male and female. Conclusion Health education combined with oral rehydration salt can improve the symptoms of orthostatic intolerance in children with OH.
【学位授予单位】：中南大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R725.4
【参考文献】
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1 Praveen Kumar;胡春艳;王成;刘晓燕;吴礼嘉;李茗香;曹闽京;林萍;崔晓丽;;儿童不明原因胸闷和(或)胸痛与直立倾斜试验的关系[J];实用儿科临床杂志;2009年01期
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