脑电双频指数在儿童机械通气镇静监测中的相关性研究

发布时间：2018-10-29 19:47

【摘要】：目的:观察脑电双频指数(bispectral index,BIS)监测与镇静评分的相关性,研究其评估机械通气患儿镇静深度的可行性。方法:回顾性分析2014年7月—2015年6月入住南京医科大学附属儿童医院重症监护病房(pediatric intensive care unit,PICU)并接受机械通气的52例患儿,治疗期间均静脉咪达唑仑维持镇静,每4 h镇静唤醒1次,分别在达到镇静目标时、1 h、2 h、4 h、6 h、8 h、10 h、12 h记录BIS值、Ramsay评分、Riker镇静-躁动评分(sedation-agitation scale,SAS),就BIS值与镇静评分间进行相关分析。结果:BIS值与主观评分间相关性良好,BIS值与Ramsay评分呈负相关(r=-0.611,P0.01),与SAS评分呈正相关(r=0.599,P0.01)。结论:BIS监测可以连续、客观、实时地反映机械通气患儿的镇静状态,并能指导镇静,保证机械通气治疗安全、有效。
[Abstract]:Objective: to observe the correlation between bispectral index (bispectral index,BIS) and sedation score, and to evaluate the feasibility of sedation depth in children with mechanical ventilation. Methods: 52 children admitted to intensive care unit (pediatric intensive care unit,PICU) of Children's Hospital affiliated to Nanjing Medical University from July 2014 to June 2015 were treated with mechanical ventilation. Once every 4 h, the BIS, Ramsay, Riker sedation and restlessness (sedation-agitation scale,SAS) were recorded at 1 h, 2 h, 4 h, 6 h, 8 h, 10 h and 12 h, respectively. The correlation between BIS and sedation score was analyzed. Results: there was a good correlation between the BIS value and the subjective score. The BIS value was negatively correlated with the Ramsay score (r = -0.611, P 0.01), and was positively correlated with the SAS score (r = 0.599, P 0.01). Conclusion: BIS monitoring can reflect the sedation state of children with mechanical ventilation continuously, objectively and in real time, and can guide sedation and ensure the safety and effectiveness of mechanical ventilation therapy.
【作者单位】：南京医科大学附属儿童医院重症医学科PICU;
【基金】：南京医科大学科技发展基金(NJMU160)
【分类号】：R720.597

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