原发性肾病综合征患儿出生及发病时间的运气规律研究

发布时间：2018-11-04 10:26

【摘要】：运气学说是一门古老而经典的学科。它借助“天人相应”的中医整体观作为学术核心指导思想,阴阳五行生克承制为基本理论,十天干十二地支作为运算推演的符号,以推测宇宙天象、自然界气象、物候以及人体正常的生理和疾病状态下的病理变化。通过挖掘自然现象和生物生命征象统一性,探求两者间的内在本质联系,它揭示了疾病的发病特性并提出与之相对应的预防治疗措施。历代以来,不少医家将其应用于临床医疗实践,指导疾病的预防和治疗,并取得重要成果。目的：本课题通过回顾性分析不同年龄组别原发性肾病综合征患儿出生及发病时间上的运气学差异,探讨该病的运气学规律,以期指导该病的临床诊治,同时为运气学说应用于小儿疾病研究积累经验。方法：收集2011年-2014年间广东省中医院儿科住院部原发性肾病综合征患儿117例,依发病年龄进行分组,根据患儿的出生及发病相关时间,按运气学理论推算其出生及发病时相关运气学指标,对数据进行统计分析,得出小儿原发性肾病综合征出生及发病的运气学特点,并比较不同年龄组别患儿出生及发病时间运气学规律差异性。结果：原发性肾病综合征患儿,多出生于岁运为金运太过、水运不及和土运不及之年,客气为太阴湿土所主之时；疾病好发于岁运为火运不及、水运不及和土运太过之年,客运为太水、太土所主之时。通过对相关指标进行组间分布差异性分析,发现出生岁运为金运太过在1-3岁组和4-7岁组两组患儿间分布有显著性差异；出生客运为少水在小于4岁(1-3岁组)和大于等于4岁(4-7岁组加8-14岁组)两组间分布有显著性差异；出生客气为少阳相火在1-3岁组和4-7岁组两组患儿间分布有显著性差异；发病客运中的少土在1-3岁组和4-7岁组两组患儿间分布有显著性差异。结论：本研究提示广东地区小儿肾病综合征的发病高峰为1-3岁；在出生及发病两方面,小儿原发性肾病综合征的全年龄段运气学规律与其中1-3岁组患儿的运气规律基本相似,同时不同年龄组别间患儿的运气学规律存在一定差异。根据研究结果,推测小儿原发性肾病综合征运气学相关气候特点以影响脾肾二脏功能为主,基本符合中医“同气相求”的疾病发病观,并推测原发性肾病综合征患儿多出生于天干为庚、辛、己年份,疾病好发于天干为癸、辛、甲年份。
[Abstract]:The theory of luck is an ancient and classical subject. With the help of the whole view of "the correspondence between Heaven and Man" as the core guiding ideology of the academic study, Yin and Yang as the basic theory, and ten days as the symbol of operation and deduction, it can speculate on the cosmic phenomena and natural meteorology. Phenology and normal physiological and pathological changes in the human body. By excavating the unity of natural phenomena and biological signs, and exploring the intrinsic relationship between the two, it reveals the characteristics of disease and puts forward corresponding preventive and therapeutic measures. Since the past dynasties, many doctors have applied it to clinical medical practice, guiding the prevention and treatment of diseases, and achieved important results. Objective: to analyze the difference of luck in birth and onset time of children with primary nephrotic syndrome (PNS) in different age groups, and to explore the rule of luck in order to guide the clinical diagnosis and treatment of the disease. At the same time, accumulated experience for the application of the theory of luck in the study of pediatric diseases. Methods: from 2011 to 2014, 117 children with primary nephrotic syndrome in the department of pediatrics of Guangdong traditional Chinese Medicine Hospital were divided into groups according to the age of onset, according to the birth of the children and the time associated with the disease. According to the theory of luck, the relative luck indexes of birth and onset were calculated, and the data were statistically analyzed, and the characteristics of birth and pathogenesis of children with primary nephrotic syndrome were obtained. At the same time, the difference of birth and onset time of children with different age groups was compared. Results: the children with primary nephrotic syndrome were mostly born in the age of too much gold, water transport and earth transport is not enough years, you are too wet soil is the main time; Disease can occur when fire is too bad, water is too bad and earth is too late, and passenger transport is too water, too much. Through the analysis of the distribution difference among the related indexes, it was found that there were significant differences in the distribution of Jinyuntai between the 1-3 and 4-7 age groups. There was a significant difference in the distribution of less water between the two groups (< 4 years old (1-3 years old) and > 4 years old (4-7 years group plus 8-14 years old group); The distribution of Shaoyang phase fire in 1-3 years old group and 4-7 years old group had significant difference, and there was significant difference between 1-3 years old group and 4-7 years old group in the distribution of little soil in passenger transportation. Conclusion: this study suggests that the peak incidence of nephrotic syndrome in children in Guangdong area is 1-3 years old. In the aspect of birth and pathogenesis, the law of luck in children with primary nephrotic syndrome is similar to that of children aged 1-3 years, and there are some differences in the laws of luck among children of different age groups. According to the results of the study, it is inferred that the climatic characteristics related to luck in children with primary nephrotic syndrome are mainly related to the function of spleen and kidney, and basically accord with the disease pathogenesis view of TCM. It was inferred that the children with primary nephrotic syndrome were born in Tianxan as G, X, D, A.
【学位授予单位】：广州中医药大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R272

【参考文献】