克拉玛依市3-14岁儿童麻疹、腮腺炎、白喉、乙肝、甲肝抗体水平分析

发布时间：2018-11-05 18:16

【摘要】：目的了解克拉玛依市免疫规划疫苗针对传染病的抗体水平,为进一步做好免疫规划工作提供科学依据。方法采用分层整群随机抽样调查法,抽取克拉玛依市3-14岁249名儿童,开展麻疹、腮腺炎、白喉、乙型肝炎(简称乙肝)和甲型肝炎(简称甲肝,)Ig G抗体水平检测。结果抗体阳性率依次为麻疹97.99%、甲肝96.38%、白喉91.16%、腮腺炎86.35%和乙肝76.71%,麻疹、腮腺炎、白喉GMC(几何抗体平均浓度)分别为1 303.59 m IU/m L、707.91 U/m L、1.03 IU/m L。不同地区白喉抗体阳性率有统计学意义(=29.686,P0.001);不同免疫剂次儿童白喉、甲肝抗体阳性率有统计学意义(白喉=14.969,甲肝=9.906,P0.05)。不同年龄组、不同性别儿童麻疹、腮腺炎、白喉、乙肝、甲肝抗体阳性率均无统计学意义(P0.05);结论克拉玛依市3-14岁儿童麻疹、白喉、甲肝、腮腺炎具有较高的免疫水平,已达到卫生部规定的目标(85%),但乙肝抗体略低,建议对抗体水平低的儿童及时采取加强免疫,以提高人群的免疫屏障。
[Abstract]:Objective to understand the antibody level of immunization planning vaccine against infectious diseases in Karamay, and to provide scientific basis for further immunization planning. Methods A stratified cluster random sampling method was used to detect the antibody levels of measles, mumps, diphtheria, hepatitis B and hepatitis A (hepatitis A) in 249 children aged 3 to 14 years in Karamay. Results the positive rate of antibody was 97.99% of measles, 96.38% of hepatitis A, 91.16% of diphtheria, 86.35% of mumps and 76.71% of hepatitis B, measles and mumps. The average geometric antibody concentration of diphtheria GMC was 1 303.59 m IU/m / L ~ (707.91) U / m / L ~ (1.03) IU/m / L, respectively. The positive rate of diphtheria antibody in different areas was statistically significant (= 29.686 P0.001), and the positive rate of hepatitis A antibody in children with different immunological agents was statistically significant (diphtheria = 14.969, hepatitis A = 9.906P 0.05). The positive rates of measles, mumps, diphtheria, hepatitis B and hepatitis A antibody in children of different age groups were not statistically significant (P0.05). Conclusion the measles, diphtheria, hepatitis A and mumps of children aged 3 to 14 years old in Karamay have a high immune level, which has reached the target set by the Ministry of Health (85%), but the antibody to hepatitis B is slightly lower. It is suggested that children with low antibody level should be immunized in time to improve the immune barrier.
【作者单位】：新疆克拉玛依市疾病预防控制中心;
【基金】：克拉玛依市科技项目(SK2014-54)
【分类号】：R186

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