新生儿科住院患儿医院感染病原学特点、危险因素及预防对策分析
发布时间：2018-11-18 09:35
【摘要】：目的探究新生儿科住院患儿医院感染的病原学特点及危险因素,进一步形成有效预防对策。方法选择2015年10月-2016年10月医院新生儿科收治的3370例新生儿作为研究对象,回顾分析胎龄、出生体质量、侵入性操作、感染前使用抗菌药物或激素、喂养方式、分娩方式、住院时间等资料,探究病原学特点,并对新生儿院内感染的危险因素进行单因素及多因素分析,形成有效预防对策。结果 3370例新生儿共发生医院感染60例,感染率为1.78%;共培养病原菌60株,其中革兰阴性菌38株占63.33%,以肺炎克雷伯菌为主,革兰阳性菌19株占31.67%,以葡萄球菌为主,真菌3株占5.00%;多因素logistic研究结果显示,胎龄37周、非自然分娩、出生体质量2500g、肠外营养、侵入性操作、住院时间长以及感染前使用抗菌药物或激素等,是新生儿院内感染的独立危险因素。结论通过对新生儿院内感染临床资料分析,探究病原学特点和危险因素,总结有效预防措施,以减少新生儿院内感染。
[Abstract]:Objective to explore the etiological characteristics and risk factors of nosocomial infection in neonatal hospitalized children and to form effective preventive measures. Methods from October 2015 to October 2016, 3370 newborns were selected and analyzed retrospectively, such as gestational age, birth weight, invasive operation, use of antibiotics or hormones before infection, feeding mode and delivery mode. In order to find out the etiological characteristics and analyze the risk factors of nosocomial infection in neonates, the effective preventive measures were formed. Results there were 60 cases of nosocomial infection in 3370 newborns, and the infection rate was 1.78%. Among the 60 strains of pathogenic bacteria cultured, 38 were Gram-negative bacteria (63.33), mainly Klebsiella pneumoniae, 19 Gram-positive bacteria (31.67m), mainly Staphylococcus (Staphylococcus), and 3 fungi (5.00%). The results of multivariate logistic study showed that gestational age of 37 weeks, unnatural delivery, birth weight of 2500g, parenteral nutrition, invasive operation, length of stay in hospital and use of antibiotics or hormones before infection were independent risk factors of nosocomial infection. Conclusion by analyzing the clinical data of neonatal nosocomial infection, the etiological characteristics and risk factors are explored, and effective preventive measures are summarized to reduce neonatal nosocomial infection.
【作者单位】： 宁波市妇女儿童医院新生儿科;
【基金】：浙江省医药卫生科技计划基金资助项目(2013KYB240)
【分类号】：R197.323;R722.13
，
本文编号：2339666
[Abstract]:Objective to explore the etiological characteristics and risk factors of nosocomial infection in neonatal hospitalized children and to form effective preventive measures. Methods from October 2015 to October 2016, 3370 newborns were selected and analyzed retrospectively, such as gestational age, birth weight, invasive operation, use of antibiotics or hormones before infection, feeding mode and delivery mode. In order to find out the etiological characteristics and analyze the risk factors of nosocomial infection in neonates, the effective preventive measures were formed. Results there were 60 cases of nosocomial infection in 3370 newborns, and the infection rate was 1.78%. Among the 60 strains of pathogenic bacteria cultured, 38 were Gram-negative bacteria (63.33), mainly Klebsiella pneumoniae, 19 Gram-positive bacteria (31.67m), mainly Staphylococcus (Staphylococcus), and 3 fungi (5.00%). The results of multivariate logistic study showed that gestational age of 37 weeks, unnatural delivery, birth weight of 2500g, parenteral nutrition, invasive operation, length of stay in hospital and use of antibiotics or hormones before infection were independent risk factors of nosocomial infection. Conclusion by analyzing the clinical data of neonatal nosocomial infection, the etiological characteristics and risk factors are explored, and effective preventive measures are summarized to reduce neonatal nosocomial infection.
【作者单位】： 宁波市妇女儿童医院新生儿科;
【基金】：浙江省医药卫生科技计划基金资助项目(2013KYB240)
【分类号】：R197.323;R722.13
，
本文编号：2339666
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