支原体肺部感染患儿的临床实验室影像特征研究

发布时间：2018-11-26 11:26

【摘要】：目的探讨支原体肺部感染患儿的临床实验室影像特征,为临床及时诊治支原体肺部感染提供有效参考。方法选取2011年5月-2016年5月医院住院治疗的肺炎患儿479例,根据实验室的检测结果将患儿分为支原体肺部感染组(MPP)98例和非支原体肺部感染组(NON-MPP)381例,比较两组患儿的临床表现、实验室指标、影像学特征以及治疗后转归情况。结果 MPP组患儿的病程、发热时间均高于NON-MPP组,MPP组患儿的咳嗽评分高于NON-MPP组,且差异有统计学意义(P0.05);MPP组伴随湿Up音患儿比例低于NON-MPP组患儿,MPP组尿检异常患儿比例高于NON-MPP组患儿,差异有统计学意义(P0.05);两组患儿WBC、NET、CRP、ALT含量差异无统计学意义;MPP组患儿大片肺浸润比例、胸腔积液比例、肺不张比例、结节影比例、支气管血管束增粗比例以及淋巴结肿大的比例显著高于NON-MPP组,差异有统计学意义(P0.05);MPP组患儿的住院时间、退热时间、咳嗽缓解时间、湿Up音消失时间均高于NON-MPP组,且差异有统计学意义(P0.05),治疗2周后,MPP组患儿WBC含量、NET含量的差异无统计学意义,MPP组患儿出院后咳嗽超过1个月的比例显著高于NON-MPP组,且差异有统计学意义(P0.05)。结论支原体感染患儿病程长、咳嗽症状明显且恢复周期长,影像学可以有助于及时判定支原体感染,为临床及时的诊治支原体肺部感染提供了一个有效途径,值得临床推广。
[Abstract]:Objective to investigate the clinical laboratory imaging features of children with mycoplasma pulmonary infection and to provide an effective reference for clinical diagnosis and treatment of mycoplasma pulmonary infection. Methods from May 2011 to May 2016, 479 hospitalized children with pneumonia were divided into (MPP) group (98 cases) and non-mycoplasma pulmonary infection (NON-MPP) group (381 cases). The clinical manifestations, laboratory parameters, imaging features and outcome after treatment were compared between the two groups. Results the course of disease and febrile time in MPP group were higher than those in NON-MPP group, and the cough score in MPP group was higher than that in NON-MPP group, and the difference was statistically significant (P0.05). The proportion of children with wet Up sound in MPP group was lower than that in NON-MPP group, and the proportion of abnormal urine test in MPP group was higher than that in NON-MPP group (P0.05). There was no significant difference in WBC,NET,CRP,ALT content between the two groups. The proportion of large lung infiltration, pleural effusion, atelectasis, nodular shadow, bronchovascular bundle thickening and lymphadenopathy in MPP group were significantly higher than those in NON-MPP group (P0.05). The hospitalization time, antipyretic time, cough remission time and wet Up sound disappearance time in MPP group were significantly higher than those in NON-MPP group (P0.05). After 2 weeks of treatment, WBC content in MPP group was significantly higher than that in NON-MPP group. There was no significant difference in NET content. The rate of cough more than 1 month after discharge in MPP group was significantly higher than that in NON-MPP group (P0.05). Conclusion Mycoplasma infection children have long course of disease, obvious cough symptoms and long recovery period. Imaging can help to judge mycoplasma infection in time and provide an effective way for clinical diagnosis and treatment of mycoplasma pulmonary infection, which is worthy of clinical promotion.
【作者单位】：滨州医学院附属医院儿童呼吸与重症科;滨州市人民医院普外一科;菏泽市立医院儿科;
【基金】：山东省医药卫生科技发展计划项目(2013WS0312)
【分类号】：R725.6

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