济宁市第一人民医院二十年肛门直肠畸形患儿回顾性分析

发布时间：2018-11-28 14:12

【摘要】：目的探讨先天性直肠肛门畸形术后大便功能障碍原因,分析其相关危险因素。方法回顾性研究1994年1月至2014年1月我院手术治疗先天性直肠肛门畸形306例患儿资料,根据其术后是否存在大便功能障碍分为功能障碍组(87例)和功能良好组(219例)。从年龄、性别、临床分型、手术方式、手术次数、合并畸形、手术时间、合并瘘管等相关因素进行Logistic回归分析,探讨导致术后大便障碍的危险因素。结果306例患儿资料,其中有87例患儿术后出现不同程度的大便功能障碍,约占28.33%。95例患儿伴发畸形,占44.17%,其中泌尿系统畸形有34人次,占35.79%；生殖系统畸形有31人次,占32.63%；心血管畸形有12人次,占12.63%；神经系统畸形有8人次,占8.42%；运动系统畸形6人次,占6.32%；其他畸形4人次,占4.21%。单因素、多因素Logistic回归分析均显示临床分型、手术方式、手术次数、合并畸形4个因素与术后大便功能障碍有显著相关性(P0.05),其余因素均无统计学意义。结论先天性直肠肛门畸形术后大便功能障碍的发生与临床分型、手术方式、手术次数、合并畸形有着明显相关性。
[Abstract]:Objective to investigate the causes of defecation dysfunction after operation of congenital anorectal malformation and analyze its related risk factors. Methods from January 1994 to January 2014, 306 cases of congenital rectal and anal malformation were treated by operation in our hospital. According to whether there were defecation dysfunction after operation, we divided them into two groups: 87 cases of dysfunction group and 219 cases of good function group. Logistic regression analysis was carried out on age, sex, clinical type, operation mode, times of operation, complicated malformation, operation time and fistula. The risk factors of postoperative defecation disorder were discussed. Results among 306 cases, 87 cases had different degree of defecation dysfunction, accounting for 28.33% of 95 cases (44.17%), among which 34 cases (35.79%) had urinary system malformation. There were 31 malformations of the reproductive system (32.63), 12 of the cardiovascular malformations (12.63), 8 of the malformations of the nervous system (8.42), 6 of the deformities of the motor system (6.32); Other deformities were 4 times (4.21%). Univariate and multivariate Logistic regression analysis showed that there were significant correlations between the four factors of clinical classification, operation mode, times of operation and complicated deformity (P0.05), but no statistical significance in the other factors. Conclusion the occurrence of postoperative defecation dysfunction in patients with congenital anorectal malformation has a significant correlation with clinical type, operation mode, times of operation and complicated malformation.
【学位授予单位】：山东大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R726.5

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