祛风清肺化痰平喘法治疗小儿喘息性支气管炎热哮证的临床研究

发布时间：2019-02-16 04:38

【摘要】：目的：评价具有祛风清肺化痰平喘作用的中药汤剂配合西药治疗小儿喘息性支气管炎热哮证的可行性及有效性,为临床运用该法治疗小儿喘支提供参考依据及研究方向。方法：本研究选取喘息性支气管炎热哮证患者60例,随机分为治疗组和对照组,两组各30例,对照组给予静滴氢化可的松琥珀酸钠、氨茶碱、炎琥宁,雾化吸入布地奈德及特布他林治疗；治疗组在对照组治疗的基础上加服具有祛风清肺、化痰平喘作用的中药汤剂。两组疗程均为7天。疗程结束后,观察治疗前后喘息、咳嗽、咯痰痰鸣、鼻煽、哮鸣音、体温、精神、面色、口渴、食欲、二便、舌质、舌苔、汗出、脉象等症状体征的改善情况,以临床积分为依据观察其疗效。结果：两组患儿治疗前在性别、年龄、病情程度、主症积分、次症积分、主次症总积分等方面,差异均无统计学差异(P0.05),具有可比性。两组患儿治疗后主症改善情况比较,治疗组在改善患儿喘息、咳嗽、咯痰痰鸣、肺部哮鸣音等症状及体征方面,优于对照组,差异有统计学意义(P0.05)；在改善鼻煽方面,差异无统计学意义(P0.05)。两组患儿治疗后次症改善情况比较,在面色、食欲、大便、舌质、舌苔、汗出、脉象症状体征改善方面,差异有统计学意义(P0.05)；在体温、精神、口渴、小便改善方面,差异无统计学意义(P0.05)。两组主症积分、次症积分、主次症总积分治疗前后组内比较,差异均有统计学意义(P0.01)；治疗后两组组间比较差异有统计学意义(P0.01),治疗组优于对照组。两组综合疗效比较,差异有统计学意义(P0.05),治疗组优于对照组。结论：祛风清肺化痰平喘法配合西医疗法治疗小儿喘息性支气管炎热哮证具有一定的优势,是一种可行、有效的方法,在改善患儿喘息、咳嗽、咯痰痰鸣、哮鸣音、面色、食欲、大便、舌质、舌苔、汗出、脉象等症状方面及主症积分、次症积分、总积分变化情况比较,治疗组优于对照组。
[Abstract]:Objective: to evaluate the feasibility and effectiveness of traditional Chinese medicine decoction combined with western medicine in treating children with asthmatic bronchitis and heat asthma, and to provide reference basis and research direction for clinical treatment of asthmatic bronchitis in children. Methods: sixty patients with asthmatic bronchitis were randomly divided into treatment group and control group, 30 cases in each group. The control group was given hydrocortisone sodium succinate, aminophylline and Yanhuning. Inhalation of budesonide and terbutaline; The treatment group in the control group on the basis of the treatment plus with dispelling wind to clear the lung, phlegm antiasthmatic effect of traditional Chinese medicine decoction. The course of treatment was 7 days in both groups. After the course of treatment, the improvement of symptoms and signs, such as wheezing, cough, phlegm, nasal fan, wheezing, body temperature, spirit, facial color, thirst, appetite, stool, tongue quality, tongue coating, sweating, pulse and so on, were observed before and after the treatment. The curative effect was observed on the basis of clinical integral. Results: there was no statistical difference between the two groups in sex, age, degree of illness, main symptom score, secondary symptom score and total score of primary and secondary symptoms before treatment (P0.05). The improvement of the main symptoms after treatment in the treatment group was better than that in the control group (P0.05) in improving the symptoms and signs of wheezing, cough, phlegm and phlegm, lung wheezing and other symptoms and signs of the children in the treatment group (P0.05). In improving nasal fan, there was no significant difference (P0.05). The improvement of symptoms after treatment in the two groups, in facial color, appetite, stool, tongue, tongue coating, sweating, pulse symptoms and signs improvement, the difference was statistically significant (P0.05); There was no significant difference in body temperature, spirit, thirst and urine improvement (P0.05). There were significant differences between the two groups before and after treatment (P0.01), the difference between the two groups was statistically significant (P0.01), the treatment group was better than the control group (P0.01). Two groups comprehensive curative effect comparison, the difference has the statistical significance (P0.05), the treatment group is superior to the control group. Conclusion: the method of expelling wind and clearing the lung and removing phlegm and relieving asthma combined with western medicine therapy has certain advantages in treating children with asthmatic bronchitis and heat asthma. It is a feasible and effective method in improving the children's breathing, coughing, phlegm, wheezing and complexion. The changes of appetite, defecation, tongue quality, tongue coating, sweating, pulse and other symptoms, main symptom score, secondary symptom score and total integral were better in the treatment group than in the control group.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R725.6

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