极低出生体质量儿发生院内感染的危险因素分析

发布时间：2019-03-10 21:09

【摘要】：目的探讨极低出生体质量儿发生院内感染的危险因素。方法回顾性分析2012年2月—2015年12月于永康市妇幼保健院出生的极低出生体质量儿共114例,根据是否发生院内感染分为感染组和非感染组,根据两组患儿的一般资料和相关检查结果分析其发生院内感染的危险因素。结果共47例感染患儿,35例标本[痰液、尿液、粪便、经外周静脉置入中心静脉导管(PICC)末端、气管导管末端]培养阳性,12例标本培养阴性,标本培养阳性率80.9%。其中革兰阴性菌占88.6%,革兰阳性菌占11.4%。两组患儿的比较中,其中剖宫产、性别、体质量、胎膜早破(18 h)、宫院内感染、低血糖、低体温、出生窒息、出生气管插管、持续正压通气、PICC置管和PICC置管时间(14 d)比较,差异均无统计学意义(P0.05)。单因素分析显示,胎龄、住院时间和输血比较,差异有统计学意义(P0.05)。多因素Logistic回归分析显示,住院时间[OR=0.567,95%CI(1.028,1.842)]和输血[OR=2.319,95%CI(1.427,4.523)]是极低出生体质量儿院内感染的危险因素。结论住院时间和输血是极低出生体质量儿发生院内感染的危险因素。
[Abstract]:Objective to investigate the risk factors of nosocomial infection in very low birth mass infants. Methods 114 cases of very low birth weight infants born in Yongkang Maternal and Child Health Hospital from February 2012 to December 2015 were analyzed retrospectively. They were divided into infection group and non-infection group according to the incidence of nosocomial infection. The risk factors of nosocomial infection were analyzed according to the general data and related examination results of the two groups. Results among 47 infected children, 35 samples (sputum, urine, feces) were positive for (PICC) end of central venous catheter and end of trachea catheter, 12 cases were negative, and the positive rate of specimen culture was 80.9%. Gram-negative bacteria accounted for 88.6%, Gram-positive bacteria accounted for 11.4%. Among the two groups, cesarean section, sex, body mass, premature rupture of membranes (18 h), intrauterine infection, hypoglycemia, hypothermia, birth asphyxia, birth tracheal intubation, continuous positive pressure ventilation), There was no significant difference between PICC and PICC in 14 days (P0.05). Univariate analysis showed that there were significant differences in gestational age, hospitalization time and blood transfusion (P0.05). Multivariate Logistic regression analysis showed that hospital stay [OR=0.567,95%CI (1.028, 1.842)] and blood transfusion [OR=2.319,95%CI (1.427, 4.523)] were risk factors for in-home infection of very low birth weight. Conclusion hospitalization time and blood transfusion are risk factors for nosocomial infection in very low birth mass infants.
【作者单位】：浙江省永康市妇幼保健院新生儿科;
【分类号】：R722.6

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