早产儿窒息的相关因素分析

发布时间：2019-04-02 19:11

【摘要】：目的：探讨早产儿窒息的相关因素，为早产的治疗提供相关临床指导。方法： 1.对2012年1月至2014年2月在重庆医科大学附属第二医院产科住院分娩的早产病例按孕妇年龄、孕周、合并症、分娩方式以及是否合并胎膜早破进行统计，采用Logistic回归分析上述因素与早产儿窒息的关系。 2.对185例未足月胎膜早破病例按破膜时间进行分组，矫正其他相关因素对早产儿窒息的影响后，评价胎膜早破破膜时间对早产儿窒息的影响。结果：共收集早产相关病例589例，排除不合格病历43例，排除双胎病例92例，选择符合要求454例早产病例纳入统计，结果如下： 1.孕妇的年龄对早产儿缺氧窒息无明显影响（p0.05）。 2.孕周越小，早产儿发生缺氧窒息的概率越大(p0.05，回归系数为-0.8939)。 3.孕妇合并HDCP、GDM、ICP、甲状腺功能低下、甲状腺功能亢进、先天性心脏病、瘢痕子宫等合并症明显影响早产儿窒息率，母亲孕期具有合并症的早产儿发生窒息的概率是无合并症早产儿的3.832倍（p0.05,OR值=3.832）。 4.胎儿分娩方式明显影响早产儿窒息率，以剖宫产方式分娩的早产儿发生缺氧窒息的概率是以阴道分娩的早产儿的2.125倍(p0.05,OR值=2.125)。 5.胎膜早破对早产儿窒息的发生率无明显影响（p0.05），但破膜时间影响早产儿发生窒息的概率，不同破膜时间对早产儿发生窒息的概率有明显差异，破膜时间越长，早产儿窒息的发生率越大（p0.05，，回归系数为0.5339）。结论：胎儿孕周、分娩方式、孕妇是否存在合并症以及破膜时间的长短均是影响早产儿窒息的因素，而孕妇年龄对早产儿窒息发生没有明显影响。
[Abstract]:Objective: to explore the related factors of asphyxia in preterm infants and to provide clinical guidance for the treatment of preterm labor. Methods: 1. The number of premature deliveries in the second affiliated Hospital of Chongqing Medical University from January 2012 to February 2014 was calculated according to the age of the pregnant woman, gestational week, complications, mode of delivery and whether premature rupture of membranes occurred or not, Logistic regression was used to analyze the relationship between the above factors and asphyxia of preterm infants. 2. 185 cases of premature rupture of membranes were divided into groups according to the time of rupture of membranes. After correcting the influence of other related factors on asphyxia of premature infants, the effect of rupture time of premature membranes on asphyxia of preterm infants was evaluated. Results: a total of 589 cases related to preterm delivery were collected, 43 cases of unqualified medical records were excluded, 92 cases of twin births were excluded, 454 cases of premature delivery were selected and included in the statistics. The results are as follows: 1. The age of pregnant women had no significant effect on hypoxic asphyxia of preterm infants (p0.05). 2. The smaller the gestational age was, the higher the probability of hypoxic asphyxia occurred in premature infants (p 0.05, regression coefficient was-0.8939). 3. Pregnant women with HDCP,GDM,ICP, hypothyroidism, hyperthyroidism, congenital heart disease, scar uterus and other complications significantly affect the rate of premature asphyxia. The incidence of asphyxia in preterm infants with complications during pregnancy was 3.832 times higher than that in non-concomitant preterm infants (p 0.05, OR = 3.832). 4. The rate of premature asphyxia was significantly affected by the mode of fetal delivery. The probability of hypoxic asphyxia in preterm infants delivered by cesarean section was 2.125 times higher than that in preterm infants who were delivered by vagina (p 0.05, OR = 2.125). 5. Premature rupture of membranes had no significant effect on the incidence of asphyxia in preterm infants (p0.05), but the time of rupture of membranes affected the probability of asphyxia in preterm infants, and there was significant difference in the probability of asphyxia in preterm infants with different time of rupture of membranes. The higher the incidence of asphyxia in preterm infants (p 0.05, regression coefficient was 0.5339). Conclusion: gestational weeks, delivery mode, complications of pregnant women and the duration of rupture of membranes are all factors affecting asphyxia of preterm infants, but the age of pregnant women has no significant effect on the occurrence of asphyxia of preterm infants.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R722.6

【参考文献】