晚期早产儿早期智能发育结局的研究

发布时间：2019-04-15 11:55

【摘要】：目的探讨晚期早产儿(LPI)早期智能发育结局。方法选择2012年1月至2015年1月新生儿病房收治的出生胎龄34~36+6周、治愈出院并定期规律随访的106例早产儿为晚期早产儿组;随机抽取同期120例健康足月儿(FPI)为对照组。对校正年龄40周的晚期早产儿及40周龄的足月儿进行新生儿神经行为测定(NBNA),晚期早产儿校正龄3、6、12月龄或者足月儿3、6、12月龄时采用Gesell发育量表进行评估。结果 LPI组NBNA评分低于37分,低于FTI组(P0.05)。校正龄3月龄时,LPI组大运动、精细运动、个人社交落后于FTI组(P0.05);校正龄6月龄时,LPI组适应性、大运动、精细运动落后于FTI组(P0.05);校正年龄12月龄时,LPI组适应性、大运动、个人社交测评明显低于FTI组(P0.05)。结论晚期早产儿早期智能发育迟缓,需加强神经发育监测。
[Abstract]:Objective to investigate the outcome of early intelligent development of (LPI) in late preterm infants. Methods from January 2012 to January 2015, 106 preterm infants who were cured and regularly followed up were selected from the neonatal ward for 34 weeks to 36 6 weeks, and (FPI) for the same period were randomly selected as the control group. Neonatal neurobehavioral tests were carried out in 40-week-old preterm infants and 40-week-old full-term infants with (NBNA),. Gesell developmental scale was used to evaluate the neurobehavioral behavior of preterm infants at the correct age of 3, 6, 12 months or 3, 6, 12 months, and at 6 and 12 months of age. Results the score of NBNA in LPI group was lower than that in FTI group (P 0.05). At the age of 3 months, LPI group lags behind FTI group in big exercise, fine movement and individual sociality (P0.05); at 6 months age, LPI group lags behind FTI group in adaptability, large movement and fine movement (P0.05); When the age was adjusted for 12 months, the adaptability, large exercise and individual social evaluation of the LPI group were significantly lower than those of the FTI group (P0.05). Conclusion it is necessary to strengthen the monitoring of nerve development in advanced preterm infants with early intelligent retardation.
【作者单位】：广州医科大学附属广州市妇女儿童医疗中心新生儿科;郑州市儿童医院新生儿科;广西壮族自治区妇幼保健院新生儿科;
【基金】：广东省科技厅科技计划项目(2012B061700010)
【分类号】：R722.6

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