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幽门螺杆菌感染及其分型与儿童过敏性紫癜相关性分析

发布时间:2019-05-20 09:40
【摘要】:目的研究不同类型幽门螺杆菌(HP)感染与儿童过敏性紫癜(HSP)之间的相关性,进一步探讨HSP的病因及发病机制。方法收集2014年9月至2015年12月青岛大学附属医院儿科住院治疗的100例HSP患儿作为病例组,同时选取50名门诊健康查体同龄儿童作为对照组。进行HP抗体检测及分型检测。结果 HSP组患儿的HP感染率明显高于对照组(χ~2=4.170,P0.05)。其中有消化系症状HSP组HP感染率明显高于无消化系症状组(χ~2=12.542,P0.05);HP阳性HSP组Ⅰ型和中间型菌株总感染率明显高于HP阳性正常对照组(χ~2=8.499,P0.05);HP阳性有消化系症状HSP组Ⅰ型菌株感染率明显高于HP阳性无消化系症状组(χ~2=8.433,P0.05),Ⅱ型菌株感染率明显低于无消化系症状组(χ~2=12.046,P0.05)。结论儿童HSP的发病可能与HP感染有关。HSP儿童感染HP菌株类型以Ⅰ型、中间型为主,且与临床消化系统症状密切相关。
[Abstract]:Objective to study the relationship between different types of HP (HP) infection and (HSP) in children with Henoch-Schonlein purpura (HSP), and to explore the etiology and pathogenesis of HSP. Methods from September 2014 to December 2015, 100 children with HSP in the affiliated Hospital of Qingdao University were collected as the case group, and 50 children of the same age were selected as the control group. HP antibody detection and typing detection were carried out. Results the infection rate of HP in HSP group was significantly higher than that in control group (蠂 ~ 2 鈮,

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