养阴清肺，祛风止咳法治疗小儿过敏性咳嗽的临床研究

发布时间：2019-06-19 09:22

【摘要】：研究目的：通过观察治疗前后过敏性咳嗽主要疗效指标的变化,客观评价养阴清肺,祛风止咳法治疗小儿过敏性咳嗽阴虚证的临床疗效、安全性。研究方法：采用随机、对照的临床试验方法,将符合小儿过敏性咳嗽的66例患儿随机分为两组,中药组、西药组各33例,中药组(汤剂)：以“南沙参10g、麦冬10g、炙百部10g、法半夏6g、钩藤8g、稀签草15g、紫草15g、炙冬花10g、佛耳草10g”为主方辨证治疗。每日1剂。西药组：口服西替利嗪糖浆(贝分),临床上一般是1ml/岁,1次/天。两组均以7天为1个疗程,治疗并观察2个疗程。观察两组在治疗前后咳嗽发作频率、咳嗽程度及鼻痒、喷嚏、流涕、面色、汗出、食欲、大便等症状的改善情况。研究结果：两组在降低咳嗽发作频率、咳嗽程度方面均有疗效(P0.05),对鼻痒喷嚏、流涕、出汗、面色等的改善亦有明显疗效(P0.05),但在食欲、大便、汗出的改善方面,西药组无统计学意义(P0.05),中药组有显著统计学意义(P0.01),故较之西药组具有明显优势。两组主要症状疗效比较差异无统计学意义(P0.05),其中中药组痊愈显效率为48%,总有效率为90.91%；西药组痊愈显效率为37.50%,总有效率亦为89.50%。中医证候疗效判定中药组明显优于西药组(P0.05),其中总有效率：中药组为100%,西药组为66.67%。说明在改善过敏性咳嗽肺阴虚症候方面,中药组明显优于西药组。两组治疗期间均未见不良反应。结论：养阴清肺,祛风止咳治疗小儿过敏性咳嗽肺阴虚证是有效和安全的方法。
[Abstract]:Objective: to observe the changes of main curative effects of allergic cough before and after treatment, and to objectively evaluate the clinical efficacy and safety of nourishing yin and clearing lung and dispelling wind and relieving cough in the treatment of allergic cough yin deficiency syndrome in children. Methods: 66 children with allergic cough in children were randomly divided into two groups: traditional Chinese medicine group (n = 33), western medicine group (n = 33) and traditional Chinese medicine group (decoction). The main prescription was "Nansha ginseng 10g, Ophiopogon officinalis 10g, grilled 100 parts 10g, Pinellia ternata 6g, raspberry 8g, rare signature grass 15g, shikweed 15g, hot winter flower 10g, berbergrass 10g". One dose a day. Western medicine group: oral cetirizin syrup (shellfish), usually 1ml/ years old, once a day. Both groups were treated with 7 days as a course of treatment and observed for 2 courses. The frequency of cough, the degree of cough and the improvement of nasal itching, sneezing, runny nose, facial color, sweating, appetite and stool were observed before and after treatment. Results: the two groups were effective in reducing the frequency of cough attack and the degree of cough (P 0.05), and also had obvious effect on the improvement of nasal itching sneezing, runny nose, sweating and facial color (P 0.05), but there was no significant difference in appetite, stool and sweating in the western medicine group (P 0.05), but there was significant statistical significance in the traditional Chinese medicine group (P 0.01), so it had obvious advantages over the western medicine group. There was no significant difference in the curative effect of the main symptoms between the two groups (P 0.05). The effective rate was 48% and the total effective rate was 90.91% in the drug group and 37.50% in the western medicine group and 89.50% in the western medicine group. The curative effect of traditional Chinese medicine group was significantly better than that of western medicine group (P 0.05). The total effective rate was 100% in traditional Chinese medicine group and 66.67% in western medicine group. It shows that the traditional Chinese medicine group is obviously superior to the western medicine group in improving the syndrome of allergic cough and deficiency of lung yin. No adverse reactions were found in both groups during treatment. Conclusion: nourishing yin and clearing lung, dispelling wind and relieving cough is an effective and safe method in the treatment of allergic cough with deficiency of lung yin in children.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R272

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