安徽省芜湖市城区0~24月龄婴幼儿过敏性疾病的危险因素分析

发布时间：2019-08-09 14:18

【摘要】：目的了解安徽省芜湖城区0~24月龄婴幼儿过敏性疾病既往发病情况,探讨婴幼儿过敏性疾病的危险因素,为今后婴幼儿过敏性疾病的防治工作及发病机制的深入研究提供理论参考。方法采取整群随机抽样的方法对600名安徽省芜湖市城区0~24月龄婴幼儿母亲进行问卷调查,询问疾病史、家族史、孕期及育儿等情况,运用单因素和多因素logistic回归分析方法对资料进行分析。结果在纳入分析的597名婴幼儿中,既往被确诊为过敏性疾病者共56例(9.4%)。单因素分析显示,月龄、解热镇痛药物使用、父亲过敏史、直系祖辈亲属过敏史和孕期母亲鱼虾蟹贝类食用5项因素与既往罹患过敏性疾病相关联(P0.05)。多因素回归分析显示,月龄、父亲过敏史、直系祖辈亲属过敏史与既往罹患过敏性疾病存在正关联(OR依次为:4.0~4.9、2.7、2.4,均P0.05),而母亲孕期经常食用鱼虾蟹贝类与既往罹患过敏性疾病存在负关联(OR=0.3,P0.05)。结论过敏家族史是安徽省芜湖城区0~24月龄婴幼儿过敏性疾病发生的独立危险因素,而母亲孕期经常食用鱼虾蟹贝类是其保护因素。
[Abstract]:Objective to investigate the past incidence of allergic diseases in infants aged 0 ~ 24 months in Wuhu City, Anhui Province, and to explore the risk factors of allergic diseases in infants and young children, so as to provide theoretical reference for further study on the prevention and treatment of allergic diseases in infants and young children in the future. Methods A questionnaire survey was conducted among 600 mothers of 0 ~ 24 months old in Wuhu City, Anhui Province. The history of disease, family history, pregnancy and child rearing were investigated by cluster random sampling. The data were analyzed by univariate and multivariate logistic regression analysis. Results of the 597 infants included in the analysis, 56 (9.4%) had previously been diagnosed as allergic diseases. Univariate analysis showed that age, use of antipyretic and analgesic drugs, history of father allergy, allergic history of immediate ancestral relatives and consumption of fish, shrimp, crab and shellfish during pregnancy were associated with allergic diseases in the past (P 0.05). Multivariate regression analysis showed that there was a positive correlation between allergic history of age, father allergy history and immediate ancestor relatives (OR: 4.0 鈮，

本文编号：2524837