不同营养支持方案在极低出生体重儿中的应用效果比较

发布时间：2019-08-13 19:46

【摘要】：目的探讨不同营养支持方案在极低出生体重儿(VLBWI)中的应用效果。方法选取2014年3月-2015年12月该院收治的行早期积极营养支持方案的45例VLBWI归为早期组,然后选取2013年1月-2014年2月收治的行传统滞后静脉营养支持方案的40例VLBWI为滞后组。比较两组的临床资料、并发症发生状况及实验室检查结果。结果体重的下降幅度、恢复出生体重的时间、体重达到2 000 g的日龄、静脉营养支持的持续天数、总住院时间等均早期组滞后组,恢复出生体重后的体重平均增长速度、出生后第7天的热卡总量等早期组滞后组,差异有统计学意义(P0.05)。所有患儿均未出现氮质血症、静脉炎、血栓形成等并发症,早期组的喂养不耐受(FI)、宫外生长迟缓(EUGR)等并发症发生率低于滞后组,差异有统计学意义(P0.05)。两组的高胆红素血症、胆汁淤积、坏死性小肠结肠炎(NEC)等并发症发生率比较,差异无统计学意义(P0.05)。两组的血总胆红素(TB)、结合胆红素(CB)、血肌酐(Scr)、尿素氮(BUN)、丙氨酸氨基转移酶(ALT)等指标比较,差异无统计学意义(P0.05)。结论对VLBWI而言,早期给予积极营养支持能促进患儿的生长发育,降低FI和EUGR的发生风险,安全可行,值得临床推广应用。
[Abstract]:Objective to investigate the effect of different nutritional support schemes on (VLBWI) in very low birth weight infants. Methods from March 2014 to December 2015, 45 cases of VLBWI treated with early active nutrition support program were divided into early group, and then 40 cases of VLBWI treated with traditional delayed intravenous nutrition support program from January 2013 to February 2014 were selected as lag group. The clinical data, complications and laboratory results of the two groups were compared. Results the rate of weight loss, the time to recover birth weight, the age of 2 000 g body weight, the duration of intravenous nutrition support and the total hospitalization time were all in the early lag group, the average weight gain rate after recovery of birth weight and the total amount of heat card on the 7th day after birth, the difference was statistically significant (P 0.05). There were no complications such as azotemia, phlebitis and thrombosis in all children. The incidence of complications such as (FI), extrauterine growth retardation (EUGR) in the early group was lower than that in the lag group, the difference was statistically significant (P 0.05). There was no significant difference in the incidence of hypercholinemia, cholestasis and (NEC) between the two groups (P 0.05). There was no significant difference between the two groups (P 0.05). There was no significant difference between the two groups (P 0.05). There was no significant difference between the two groups (P 0.05). There was no significant difference between the two groups (P 0.05). Conclusion for VLBWI, early active nutritional support can promote the growth and development of children, reduce the risk of FI and EUGR, safe and feasible, and is worthy of clinical application.
【作者单位】：南方医科大学第三附属医院儿科;
【分类号】：R722.6

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