老年原发性高血压患者血压晨峰现象与靶器官损害的相关性研究

发布时间：2018-01-04 07:09

本文关键词：老年原发性高血压患者血压晨峰现象与靶器官损害的相关性研究　出处：《心血管康复医学杂志》2013年04期 　论文类型：期刊论文

更多相关文章： 高血压 血压监测 便携式 老年人

【摘要】：目的:探讨老年原发性高血压患者血压晨峰(MBPS)与靶器官损害的相关性。方法:老年原发性高血压患者292例,据24h动态血压分晨峰组(MBPS组,128例)与非晨峰组(非MBPS组,164例),检查血脂、空腹血糖、肌酐,计算人体质量指数(BMI)、行心脏和颈动脉超声检查,计算左室质量指数(LVMI)、颈动脉内膜中层厚度(IMT)。结果:与非MBPS组比较,MBPS组24h收缩压(SBP)[(138.2±13.2)mmHg比(153.1±12.1)mmHg]、白昼SBP[(143.3±12.7)mmHg比(158.2±9.1)mmHg]以及夜间SBP[(136.6±9.4)mmHg比(150.7±10.1)mmHg]均明显升高(P0.05),LVMI[(101.76±34.45)g/m2比(138.13±37.6)g/m2]、颈动脉IMT[(0.84±0.11)mm比(1.35±0.35)mm]均明显增大(P0.05);Pearson相关分析显示,血压晨峰与LVMI、IMT呈正相关(r分别=0.688,0.524,P均0.05)。结论:老年原发性高血压患者血压晨峰现象加重靶器官损害。
[Abstract]:Objective: to investigate the relationship between blood pressure (MBPSs) and target organ damage in elderly patients with essential hypertension. Methods: 292 elderly patients with essential hypertension were enrolled in this study. According to 24-hour ambulatory blood pressure (ambulatory blood pressure) and non-morning peak group (MBPS group, n = 164), blood lipids, fasting blood glucose, creatinine and body mass index (BMI) were measured. The left ventricular mass index (LVMI), carotid intima-media thickness (IMT) and carotid artery intima-media thickness (IMT) were calculated by echocardiography. Results: compared with the control group, the left ventricular mass index (LVMI) was calculated. SBP (24 h SBP) in MBPS group. [SBP was 138.2 卤13.2mHg vs 153.1 卤12.1mHg], and SBP in daytime was 138.2 卤13.2hmHg compared with 153.1 卤12.1hmHg. [143.3 卤12.7hmHg vs 158.2 卤9.1hmHg] and SBP at night. [Compared with 150.7 卤10.1 mm Hg, 136.6 卤9.4 mm Hg significantly increased P0.05 卤LVMI. [101.76 卤34.45 g / m ~ 2 vs 138.13 卤37.6 g / m ~ 2, carotid IMT. [0.84 卤0.11mm was significantly larger than 1.35 卤0.35mm. Pearson correlation analysis showed that there was a positive correlation between the morning peak of blood pressure and LVMI-IMT (0.688 卤0.524). Conclusion: the morning peak of blood pressure in elderly patients with essential hypertension aggravated the damage of target organs.
【作者单位】：周至县人民医院心内科;西安市第四医院;
【分类号】：R544.1
【正文快照】： 研究表明,正常人24h血压呈“两峰一谷”的昼夜节律变化,清晨血压的变异最为显著。据观察,在未经治疗的高血压患者,清晨6∶00至10∶00的收缩压平均升高14mmHg,甚至可上升80mmHg,国内外把这种清晨血压急剧上升的现象称作血压晨峰现象(morning blood pressure surge,MBPS)[1]。

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