减少采样b值对正常成人脑组织扩散峰度成像结果影响的研究

发布时间：2018-02-02 17:58

本文关键词： 扩散峰度成像磁共振成像采样b值　出处：《临床放射学杂志》2017年12期 　论文类型：期刊论文

【摘要】：目的通过对比扩散峰度成像(DKI)3b值与5b值扫描方法,探寻减少采样b值对正常成人脑组织DKI分析结果的影响。方法回顾性分析30名正常成人的DKI 3b值与5b值扫描数据,利用DKE软件生成平均扩散峰度(MK)、各向异性分数(FA)及平均扩散系数(MD)参数图,选取双侧灰质(额叶、颞叶、顶叶、枕叶、基底节区、背侧丘脑)及双侧白质(额叶、颞叶、顶叶、枕叶、内囊后肢、放射冠、大脑脚及胼胝体膝部、胼胝体压部)为感兴趣区(ROI)。测量并比较3b值与5b值ROI MK、FA及MD参数值。结果 DKI 3b值与5b值扫描的MK、MD、FA参数图在双侧脑灰质及白质不同ROI参数值均无统计学差异(P0.05)。结论通过减少采样b值,可以明显减少DKI数据扫描时间,且不影响对DKI结果的测量。
[Abstract]:Objective to compare the DKI 3b and 5b values of diffusion kurtosis imaging. To explore the effect of reducing the sampling b value on the DKI analysis results of normal adult brain tissue. Methods the DKI 3b and 5b scan data of 30 normal adults were analyzed retrospectively. The mean diffusion kurtosis, anisotropic fraction and average diffusion coefficient (MDD) parameters were generated by DKE software, and bilateral gray matter (frontal lobe, temporal lobe, parietal lobe, occipital lobe, basal ganglia area) were selected. Dorsal thalamus) and bilateral white matter (frontal lobe, temporal lobe, parietal lobe, occipital lobe, posterior limb of internal capsule, corona radiata, cerebral foot and genu of corpus callosum). The corpus callosum was the region of interest. The parameters of ROI MKN FA and MD were measured and compared. Results DKI 3b value and 5b value were used to scan MKN MD. There was no significant difference in the ROI parameters of bilateral gray matter and white matter between the two sides (P 0.05). Conclusion the scanning time of DKI data can be significantly reduced by reducing the sampling b value. The measurement of DKI results was not affected.
【作者单位】：南京医科大学附属南京医院(南京市第一医院)放射科;飞利浦医疗保健事业部;
【基金】：江苏省社会发展面上项目(编号:BE2017614) 南京市科委课题(编号:201503021)
【分类号】：R445.2
【正文快照】： 本研究系江苏省社会发展面上项目(编号:BE2017614);南京市科委课题(编号:201503021)作者单位:210006南京,南京医科大学附属南京医院(南京市第一医院)放射科(陈谦、陈慧铀、冯源、毛存南、王鹏、苏文、殷信道、孙军);飞利浦医疗保健事业部(卓芝政);*通讯作者5 Wilting JE,Zwart

【相似文献】