基于人脑纹状体与海马结构的断层影像学研究

发布时间：2018-02-02 22:29

本文关键词： 纹状体海马结构断层影像解剖 MRI　出处：《中国临床解剖学杂志》2015年04期 　论文类型：期刊论文

【摘要】：目的探讨纹状体与海马结构的相关性,为临床影像诊断提供形态学依据和相关测值。方法采集100例经诊断无病变的成人头部磁共振图像,按照年龄16~25、26~35、36~45、46~55、56~65岁进行分组,每组男、女各10例。观测纹状体与海马结构的面积、横径、矢径等线性指标,标准化前、后数据均进行相应统计学处理。结果数据经标准化处理后,运用单因素方差分析显示:纹状体面积无性差,尾状核头矢径、海马面积、海马横径、矢径存在性差(女性男性),颞角宽度存在性差(女性男性);尾状核头横径存在侧差(左右),壳面积、壳矢径存在侧差(左右)。利用Pearson相关分析显示:纹状体面积与年龄、颞叶钩回间距呈负相关,与颞角宽度呈正相关;海马面积与尾状核头面积、颞角宽度呈正相关。结论成年人纹状体面积随着年龄增长而缩小;海马结构与纹状体在形态结构上具有相关性;壳面积右侧大于左侧;女性海马面积大于男性;颞角宽度可以作为研究纹状体与海马结构形态变化的共同参考指标。
[Abstract]:Objective to investigate the correlation between striatum and hippocampal formation, and to provide morphological basis and relevant values for clinical imaging diagnosis. The area and diameter of striatum and hippocampal formation were observed in 10 males and 10 females in each group. The linear indexes such as sagittal diameter were statistically processed before and after standardization. Results the single factor analysis of variance showed that the area of striatum was asexual and the sagittal diameter of caudate nucleus was poor. The area of hippocampus, transverse diameter of hippocampus and sagittal diameter were poor (female male) and temporal horn width (female male); Lateral difference existed in transverse diameter of caudate nucleus (left and right, shell area, shell sagittal diameter) (left and right). Using Pearson correlation analysis, the area of striatum was negatively correlated with age and the distance between temporal lobe uncinate gyrus. There was a positive correlation with the width of temporal horn. The area of hippocampus was positively correlated with the head area of caudate nucleus and the width of temporal horn. The hippocampal structure was correlated with the striatum. The right side of the shell is larger than the left. The area of hippocampus was larger in female than in male. The width of temporal horn can be used as a common reference index to study the morphological changes of striatum and hippocampus.
【作者单位】：川北医学院解剖学教研室;川北医学院附属医院放射科;
【基金】：川北医学院科研发展计划项目(CBY-13-A-QN27)
【分类号】：R445.2
【正文快照】： 随着神经影像学检查技术的飞速发展,尤其是在中枢神经系统疾病检查中引入MRI技术,使人类对自身的活体研究成为可能。纹状体是人脑皮质下的最大神经核团,很多学者注意到多系统萎缩、帕金森病、强迫症等神经、精神疾病都会引起患者纹状体的形态学改变。而海马结构也是人脑的重要

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