声触诊组织定量技术在评定慢性乙肝患者肝纤维化程度的价值

发布时间：2018-02-04 11:52

本文关键词： 超声检查慢性乙型肝炎肝纤维化声触诊组织定量声脉冲辐射力弹性成像　出处：《南京医科大学学报(自然科学版)》2017年11期 　论文类型：期刊论文

【摘要】：目的 :探讨声辐射力脉冲成像(acoustic radiation force impulse imaging,ARFI)声触诊组织定量(virtual touch tissue quantification,VTQ)技术评价慢性乙型肝炎患者肝纤维化程度的应用价值。方法 :应用ARFI弹性成像VTQ技术定量检测66例乙型肝炎患者的肝脏组织硬度,以横向剪切波速度(shear wave velocity,SWV)表示,其结果与肝脏穿刺活检病理结果的纤维化分期对照。结果:慢性乙型肝炎患者中S0期的SWV平均值为(1.22±0.35)m/s,S1期的SWV平均值为(1.41±0.25)m/s,S2期的SWV平均值为(2.18±0.21)m/s,S3期的SWV平均值为(2.46±0.22)m/s,S4期的SWV平均值为(2.96±0.44)m/s,除了S0期与S1期SWV值差异无统计学意义(P0.05),其余各期之间两两比较,差异均有统计学意义(P均0.01)。结论 :ARFI弹性成像VTQ技术能定量反映慢性乙型肝炎患者肝纤维化分期情况,是一种能有效评估肝纤维化分期的新方法。
[Abstract]:Objective: to evaluate the value of acoustic radiation power pulse radiation force impulse imaging technique (ARFI) in evaluating the degree of hepatic fibrosis in patients with chronic hepatitis B. methods: ARFI elastography VTQ technique was used to quantify the degree of hepatic fibrosis in patients with chronic hepatitis B. Liver tissue hardness was measured in 66 patients with hepatitis B. In terms of transverse shear wave velocities per ear wave velocitysSWV), Results: in patients with chronic hepatitis B, the mean value of SWV in stage S0 was 1.22 卤0.35 mP / s ~ (-1) SWV in S _ 1 stage was 1.41 卤0.25 m 路s ~ (-1) 路s ~ (-1) SWV in S _ 2 stage was 2.18 卤0.21 m 路s ~ (-1) / s ~ (3) SWV mean value was 2.46 卤0.22 m 路s ~ (-1) / S ~ (4) stage in patients with chronic hepatitis B. The average value of SWV was 2.96 卤0.44 m / s, except that there was no significant difference in SWV between S0 and S1, but there was no significant difference between the other stages. Conclusion VTQ can quantitatively reflect the stage of hepatic fibrosis in patients with chronic hepatitis B, and is a new method to evaluate the staging of liver fibrosis.
【作者单位】：苏州市吴江区第一人民医院超声科;
【分类号】：R445.1;R512.62;R575.2
【正文快照】： 我国乙型肝炎病毒表面抗原携带者约1.2亿,每年报告新发病人数约50万,目前全国现有病毒性肝炎患者约2 800万,每年死于乙型肝炎相关的肝病患者约28万,人群中乙肝表面抗原(HBs Ag)阳性率约为7.18%,肝脏纤维化和肝硬化的主要病因是慢性乙型肝炎病毒的反复感染,临床医生治疗方案的

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