简化的关节滑膜超声评分法评估类风湿关节炎活动性的意义

发布时间：2018-02-20 22:20

本文关键词： 类风湿关节炎超声关节疾病活动性　出处：《中国超声医学杂志》2015年06期 　论文类型：期刊论文

【摘要】：目的探究简化的关节滑膜超声评分法在RA患者疾病活动性评估中的作用。方法类风湿关节炎(RA)患者116例,DAS28评分法评价疾病活动性,应用高频超声检查双侧肘关节(Elb)、腕关节(Wri)、1~5掌指关节(MCP)、1~5近端指间关节(PIP)、膝关节(Kne)、踝关节(Ank)及跖趾关节(MTP),对滑膜炎进行评分(0~3分),计算每对关节滑膜评分及所有关节滑膜评分总和。分析总滑膜评分及不同关节组合滑膜评分与DAS28之间的相关性。结果总滑膜评分与DAS28评分存在显著相关(r=0.440,P0.01);包含Wri、Elb、Kne、MCP3、MCP4、PIP3、MTP4、PIP1在内的8对关节滑膜评分与DAS28评分之间相关性最高(r=0.540,P0.01)。结论包含Wri、Elb、Kne、MCP3、MCP4、PIP3、MTP4、PIP1在内的8对关节滑膜评分可以作为简化的关节滑膜超声评分法用于评估RA的活动性。
[Abstract]:Objective to explore the role of simplified synovial ultrasonography in the assessment of disease activity in patients with RA. Methods 116 patients with rheumatoid arthritis (RA) were assessed with DAS28 score. High frequency ultrasound was used to examine the bilateral elbow with Elbor, the wrist with MCPP 1 / 5, the proximal interphalangeal joint with PIPA, the knee joint with Knen, the ankle with ankles, and the metatarsophalangeal joint with MTPN. The synovitis was scored 0 ~ 3 points, and the synovial score of each joint and all joints were calculated. The total synovial score and the correlation between the synovial score of different joint combinations and DAS28 were analyzed. Results there was a significant correlation between the total synovial score and the DAS28 score (P 0.01); eight pairs of synovium score and DAS28 score including Wrike Elbkne-MCP3MCP3MCP3MCP3MCP3MTP4PIP1. Conclusion eight pairs of joint synovial scoring including Wrigne Elb Knen MCP3MCP4 / PIP3MTP4 / PIP1 can be used as a simplified synovial ultrasonic scoring method to evaluate the activity of RA.
【作者单位】：福建医科大学附属第二医院超声科;泉州医学高等专科学校;
【基金】：福建省医学创新课题(No.2014-CXB-16) 福建省卫生厅青年课题(No.2014-2-22)
【分类号】：R593.22;R445.1

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