基于体素内不相干运动的扩散加权成像对正常及晚发型胎儿生长受限胎盘血流灌注的定量评价

发布时间：2018-02-22 04:28

本文关键词： 胎儿生长受限胎盘磁共振扩散加权成像体素内不相干运动灌注　出处：《临床放射学杂志》2017年12期 　论文类型：期刊论文

【摘要】：目的比较正常及晚发型胎儿生长受限(FGR)胎盘灌注分数的差异,探讨正常中晚孕期胎盘血液灌注量的变化规律。方法搜集60例因胎儿轻微先天性发育异常进行磁共振检查的单胎孕妇及13例产前超声疑诊FGR的孕妇,所有孕妇进行胎盘的体素不相干运动-扩散加权成像(IVIM-DWI)来计算灌注分数(f),并测量子宫动脉的搏动指数(PI)。利用线性相关分析f与孕龄及子宫动脉PI值、新生儿体重的相关性,比较正常组及晚发型FGR组f的差异。结果晚发型FGR组f值较正常晚孕组显著降低(19.07%vs 27.78%,F=17.354,P=0.000),f值与子宫动脉PI值及新生儿体重均呈显著正相关(r=0.968,P0.01;r=0.959,P0.01)。正常中晚孕组f值与孕周呈显著负相关(r=-0.534,P0.01)。结论 f值对晚发型FGR有一定的预测价值,正常妊娠中晚期胎盘灌注分数f值随孕周增加呈下降趋势。
[Abstract]:Objective to compare the difference of placental perfusion fraction between normal and late-onset fetal growth restriction (FGR). To investigate the changes of placental blood perfusion during normal middle and late pregnancy, 60 single fetus pregnant women with slight congenital abnormal development of fetus and 13 pregnant women suspected of FGR by prenatal ultrasound were collected. Placental voxel incoherent motion-diffusion weighted imaging (IVIM-DWI) was performed in all pregnant women to calculate the perfusion fraction (FV), and the pulsatility index of uterine artery was measured. The correlation of f with gestational age, uterine artery Pi and neonatal weight was analyzed by linear correlation analysis. Results compared with the normal group and the late type FGR group, the f value of the late type FGR group was significantly lower than that of the normal late pregnancy group. Results the F value of the late pregnancy group was significantly lower than that of the normal late pregnancy group. There was a significant positive correlation between the f value of the late pregnancy group and the Pi value of the uterine artery and the weight of the newborn. There was a significant positive correlation between the f value of the late pregnancy group and the gestational week. There was a significant negative correlation between rr and 0.534, P 0.01.Conclusion the value of f has certain value in predicting late onset FGR. The placental perfusion fraction (f) decreased with the increase of gestational week.
【作者单位】：南方医科大学珠江医院影像诊断科;广东省广州市番禺区何贤纪念医院放射科;广东省广州市妇女儿童医疗中心影像科;
【基金】：广州市医药卫生科技项目(编号:20161A011113)
【分类号】：R445.2;R714.5

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