13-三体综合征胎儿的孕中期超声指标分析

发布时间：2018-02-23 21:16

本文关键词： -三体综合征超声检查产前先开性畸形　出处：《中国医学影像技术》2015年06期 　论文类型：期刊论文

【摘要】：目的评估孕中期超声检查对13-三体综合征胎儿的诊断价值。方法回顾分析本院26胎经染色体核型分析确诊为13-三体综合征胎儿的声像图资料。结果前脑无裂畸形12胎(12/26,46.15%)、唇/腭裂9胎(9/26,34.62%)、室间隔缺损9胎(9/26,34.62%)、肾脏异常8胎(8/26,30.77%)、眼眶异常7胎(7/26,26.93%)、鼻发育异常5胎(5/26,19.23%)、脑室增宽4胎(4/26,15.38%)、羊水过多伴宫内生长受限2胎(2/26,7.69%)、独眼1胎(1/26,3.85%)。声像图异常率为92.31%(24/26),均表现为2种及以上异常指标。结论孕中期超声检查对诊断13-三体综合征具有一定的意义;结合染色体核型分析可提高13-三体综合征的产前诊断率,并能降低其出生率。
[Abstract]:Objective to evaluate the diagnostic value of ultrasonography in second trimester of fetal trisomy 13- syndrome. Methods a retrospective analysis of 26 fetal karyotype analysis was diagnosed with trisomy 13- syndrome fetal sonographic data. Results 12 fetal holoprosencephaly (12/26,46.15%), 9 fetal cleft lip / palate (9/ 26,34.62%), 9 ventricular septal defect fetal kidney (9/26,34.62%), 8 (8/26,30.77%), abnormal fetal fetal abnormalities in 7 eyes (7/26,26.93%), nasal dysplasia (5/26,19.23%), 5 fetal ventriculomegaly in 4 fetuses (4/26,15.38%), polyhydramnios and fetal intrauterine growth restriction (2/26,7.69%), 2 eye 1 fetal (1/26,3.85%). The abnormal rate of ultrasonography 92.31% (24/26), were more than 2 kinds of abnormal indicators. Conclusion the second trimester ultrasound examination is of great significance to the diagnosis of trisomy 13- syndrome; combined with karyotype analysis can improve the prenatal diagnosis of trisomy 13- syndrome broken rate, and can reduce the birth rate.

【作者单位】：深圳市人民医院妇产科B超室;深圳市坪山新区人民医院中心实验室;深圳市人民医院产前诊断中心;深圳市人民医院临床医学研究中心;
【基金】：广东省科技计划项目(2013B060400011) 深圳市科技创新委员会项目(JCYJ20130401093116730)
【分类号】：R714.53;R445.1

【共引文献】