磁共振延迟强化在肥厚型心肌病中的临床应用价值研究

发布时间：2018-02-24 06:29

本文关键词： 磁共振成像对比增强扫描心肌病肥厚性心功能　出处：《放射学实践》2017年12期 　论文类型：期刊论文

【摘要】：目的:探讨3.0T心脏磁共振成像(CMRI)延迟强化(LGE)序列对肥厚型心肌病(HCM)的诊断价值。方法:搜集2014年1月-2016年7月在华西医院确诊为HCM的121例患者的临床资料和CMR图像。将患者的临床资料包括性别、年龄,有无心悸、胸闷、胸痛、呼吸困难、晕厥和心脏杂音及纽约心功能分级(NYHA)等纳入分析。采用心脏功能分析软件对CMRI图像进行后处理,测量左心室壁最大厚度(LVMWT)、左、右心室舒张末期容积(EDV)、收缩末期容积(ESV)、射血分数(EF)、每搏输出量(SV)和左心室心肌质量(LVMM)。根据美国心脏病协会左室壁17节段分析方法,对121例患者的2057个心肌节段进行评价。比较有LGE组和无LGE组的临床资料及CMRI参数的差异,评价LGE节段数与LVMWT和心功能分级的相关性。结果:121例HCM患者中LGE(+)91例(75.2%)共456个节段(456/2057);LGE(+)最常见于节段2和8,分别占11.6%(53/456)和11.4%(52/456)。LGE形态:表现为局限性强化70例(70/91),弥漫性强化21例(21/91)。LGE(+)组较LGE(-)组患者的年龄偏小[分别为(48.59±14.80)和(58.93±12.79)岁]、胸痛症状出现率更低(分别为22.0%和27.3%)、LVMWT值更大[分别为(2.42±0.64)和(2.05±0.37)cm],差异均有统计学意义(P0.05)。LGE(+)节段数与LVMWT、NYHA、LVMM和LVESV均呈正相关(r值分别为0.437、0.544、0.267和0.245,P值分别为0.000、0.000、0.003和0.007),与患者年龄、LVEF和RVEF呈负相关(r值分别为-0.231、-0.244和-0.184,P值分别为0.011、0.007和0.043)。结论:3.0T心脏MRI有助于HCM患者的诊断和心功能的评估。
[Abstract]:Objective: to evaluate the diagnostic value of 3.0T delayed enhanced Mr imaging (CMRI) sequence in patients with hypertrophic cardiomyopathy (HCM). Methods: from January 2014 to July 2016, the clinical data and CMR images of 121 patients with HCM diagnosed in West China Hospital were collected. Like. Include the patient's clinical data including gender, Age, palpitation, chest tightness, chest pain, dyspnea, syncope and cardiac murmur, and New York cardiac function grading were included in the analysis. CMRI images were postprocessed with cardiac function analysis software. Right ventricular end-diastolic volume (EDV), end-systolic volume (ESVV), ejection fraction (EFF) and left ventricular mass (LVMM). 2057 myocardial segments of 121 patients were evaluated. The clinical data and CMRI parameters of LGE group and non-#en1# group were compared. To evaluate the correlation between the number of LGE segments and the LVMWT and cardiac function grade. Results in 121 HCM patients, there were 456 segments 456 / 2057 LGEs, accounting for 11.66% 53 / 456 and 11.442% 52456U 路LGE: 70 cases with localized enhancement, 7091%, diffuse. The age of 21 patients with enhanced 21 / 91 + L GE (n = 21) group was younger than that of the LGE-group [48.59 卤14.80 years and 58.93 卤12.79 years, respectively], and the incidence of chest pain was lower (22.0% and 27.3% respectively) (2.42 卤0.64 and 2.05 卤0.37 cm, respectively). There were significant differences in the number of LGE (P < 0.05) and the number of LVMWT-NYHA LVMM and LVESV. The positive correlation values were 0.437t 0.544U 0.267 and 0.245U P 0.0000.0000.0000.003 and 0.007, respectively, and negatively correlated with the age of patients with HCM and RVEF were -0.231- 0.244 and -0.184P respectively 0.0110.007 and 0.0430.Conclusion the ratio of MRI is helpful to the diagnosis and evaluation of cardiac function in patients with HCM (P < 0.05), and the positive correlation is -0.231- 0.244 and -0.184 (P < 0.05), respectively. [WT5HZ] [WT5 "BZ] [WT5" BZ] [WT5 "BZ] [WT5" BZ]
【作者单位】：四川大学华西医院放射科;成都市第三人民医院放射科;
【分类号】：R445.2;R542.2

【相似文献】