纯磨玻璃密度肺腺癌病灶内部CT影像特点

发布时间：2018-02-25 17:31

本文关键词： 肺肿瘤腺癌体层摄影术 X线计算机　出处：《实用医学杂志》2017年04期 　论文类型：期刊论文

【摘要】：目的:探讨肺腺癌纯磨玻璃密度结节(pure ground-glass opacity,p GGO)内部CT影像学特征。方法:回顾性分析156个手术病理证实的p GGO结节内部CT影像特点。所有p GGO结节中浸润前病变58个(包括不典型腺瘤样增生及原位腺癌)、微浸润腺癌32个和浸润性腺癌66个。p GGO结节内部CT影像特征包括病变密度均匀/不均匀、空泡征、空气支气管征及病变内走行血管异常改变(血管扩张、扭曲、僵直)。结果:p GGO结节中密度不均、病变内血管异常改变在3种不同病理分型中差异有统计学意义(χ2=7.452,P=0.024;(χ2=22.615,P0.001),随着结节浸润程度的增加,病变密度不均及其内血管异常改变的发生率随之增加;空气支气管征的发生率亦随病变浸润程度的加深而增高,但其仅对于浸润前病变与浸润性病变(包括微浸润腺癌和浸润性腺癌)的鉴别诊断有价值(χ~2=4.868,P=0.027)。结论:p GGO结节内部密度不均、血管异常改变对肺腺癌不同病理类型的鉴别具有一定的价值。
[Abstract]:Objective: to investigate the internal CT imaging features of pure ground-glass opacities in lung adenocarcinoma. Methods: the internal CT features of 156 surgically and pathologically proved p GGO nodules were retrospectively analyzed. All preinvasive lesions in all p GGO nodules were analyzed retrospectively. In 58 cases (including atypical adenomatous hyperplasia and in situ adenocarcinoma, 32 microinvasive adenocarcinomas and 66. P GGO nodules), CT features included homogeneous or uneven density of lesions. Vacuole sign, air bronchus sign and abnormal changes of blood vessel (vasodilation, distortion, rigidity) were observed in the lesions. Results the density of GGO nodules was uneven. There were significant differences among the three pathological types in the abnormal changes of blood vessels in the lesions (蠂 ~ 2 ~ 2 ~ (7.452) P ~ (0.024)) (蠂 ~ (2) 2 ~ (2) 22.615 ~ (15) P _ (0.001)). With the increase of the degree of nodular infiltration, the incidence of abnormal changes in the density of lesions and the abnormal changes of the internal vessels increased. The incidence of air bronchiolus sign also increased with the degree of infiltration. However, it is of value only for the differential diagnosis of preinvasive lesions and invasive lesions (including microinvasive adenocarcinoma and invasive adenocarcinoma) (蠂 ~ 2 / P = 4.868). Conclusion the density of GGO nodules is uneven. The abnormal changes of blood vessels have certain value in differentiating different pathological types of lung adenocarcinoma.
【作者单位】：石家庄市第一医院放射科;河北医科大学第二医院放射科;
【基金】：河北省医学科学研究重点课题(编号:20160804)
【分类号】：R734.2;R730.44

【相似文献】