胎儿主动脉缩窄的超声诊断与分析

发布时间：2018-03-01 08:24

本文关键词： 胎儿超声心动图先天性心脏病主动脉缩窄血流动力学　出处：《中国超声医学杂志》2015年11期 　论文类型：期刊论文

【摘要】：目的回顾性分析胎儿主动脉缩窄(CoA)的超声血流动力学参数,探讨诊断胎儿主动脉缩窄的超声比值参数诊断价值。方法选取我院行胎儿超声心动图检查,孕龄在20~38周的胎儿11 647例中,超声诊断含主动脉缩窄、主动脉峡部内径偏细的胎儿144例,根据随访结果 (病例组),选取相应孕周正常胎儿超声数据(正常组),综合分析胎儿超声心动图参数(内径比值、流速比值)在主动脉缩窄的诊断价值。结果超声诊断或提示主动脉缩窄、主动脉弓发育不良或主动脉内径偏细的144例胎儿中,成功随访53例,主动脉缩窄22例,无主动脉缩窄31例,病例组(病理阳性和病理阴性)与正常组的超声测量参数(内径比值、流速比值)均呈正态分布,方差分析显示内径比值PA/AO、AI/DA和流速比值MCA/inUA-vd、MCA/inA-RI、MCA/inUA-PI有统计学差异(P0.05)。结论胎儿超声心动图主/肺动脉内径比值参数对胎儿主动脉缩窄有重要诊断价值,脑/脐动脉血流比值参数,可为胎儿主动脉缩窄的诊断提供补充参考。
[Abstract]:Objective to retrospectively analyze the ultrasonic hemodynamic parameters of coarctation of fetal aorta and to explore the diagnostic value of the ratio parameters of ultrasound in the diagnosis of coarctation of fetal aorta. Methods Fetal echocardiography was performed in our hospital. Among 11 647 fetuses at gestational age of 20 ~ 38 weeks, 144 cases were diagnosed by ultrasonography with coarctation of aorta and thin inner diameter of aortic isthmus. According to the results of follow up (case group), the normal fetal ultrasound data (normal group) were selected, and the fetal echocardiographic parameters (ratio of inner diameter) were analyzed synthetically. Results in 144 fetuses with aortic coarctation, aortic arch dysplasia or aortic inner diameter, 53 cases were followed up successfully, 22 cases were coarctation of aorta. 31 cases without coarctation of aorta showed normal distribution of ultrasonic parameters (ratio of inner diameter and velocity) between the case group (pathological positive and pathological negative) and the normal group. The analysis of variance showed that the ratio of PA / AOA / AI / DA and the ratio of flow velocity (MCA / inUA-vdN / MCA / inUA-PI) were significantly different (P < 0.05). Conclusion Fetal echocardiography has important diagnostic value for aortic coarctation and cerebral / umbilical artery flow ratio parameters. It can provide supplementary reference for the diagnosis of fetal aortic coarctation.
【作者单位】：首都医科大学附属北京安贞医院超声科;
【基金】：胎儿心脏病母胎医学研究北京市重点实验室(No.BZ0308) 2014年度科技创新基地培育与发展工程专项项目(No.Z141107004414113)
【分类号】：R445.1;R714.5

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