常规超声与超声造影诊断甲状腺结节的Meta分析

发布时间：2018-03-02 06:03

本文关键词： 甲状腺结节超声检查超声造影造影剂 Meta分析　出处：《中国医学影像学杂志》2015年11期 　论文类型：期刊论文

【摘要】：目的超声造影(CEUS)鉴别诊断甲状腺良、恶性结节目前存在争议,本研究通过Meta分析评价CEUS对甲状腺结节的诊断价值。资料与方法在Pub Med数据库、中国知网、万方数据库中检索1990年1月—2014年12月以病理结果为"金标准"的关于常规超声、CEUS鉴别诊断甲状腺结节良恶性的中英文文献,对纳入文献进行质量评价。计算汇总敏感度、特异度及95%可信区间,并绘制汇总受试者工作特征曲线,得出Q*值。结果共纳入14篇1970个结节。常规超声、CEUS的汇总敏感度和汇总特异度分别为0.74、0.70和0.86、0.82。两者的汇总受试者工作特征曲线下面积分别为0.84、0.93,两者Q*值分别为0.77、0.86。结论 CEUS对甲状腺结节良恶性的鉴别诊断准确度较常规超声高,但两者对甲状腺结节的诊断均有重要意义,使甲状腺疾病患者避免不必要的手术治疗,对临床具有重要的诊断价值。
[Abstract]:Objective to identify benign and malignant thyroid nodules by contrast-enhanced ultrasound (CEUs). In this study, the diagnostic value of CEUS in thyroid nodules was evaluated by Meta analysis. The Chinese and English literature on the differential diagnosis of benign and malignant thyroid nodules by conventional ultrasound CEUs from January 1990 to December 2014 was searched in Wanfang database. The total sensitivity was calculated. Specificity and 95% confidence interval, and draw a summary of the subject's operating characteristics curve, The total sensitivity and specificity of conventional ultrasound CEUs were 0.74 ~ 0.70 and 0.86 ~ (0.82), respectively. The area under the operating characteristic curve was 0.840.93, and the Q* value of both was 0.77 ~ (0.86) knots. The results showed that the total sensitivity and specificity of conventional ultrasound CEUs were 0.74 ~ 0.70 and 0.86 ~ 0.82, respectively, and the area under the operating characteristic curve was 0.840.93 and 0.77 卤0.86 respectively. The accuracy of CEUS in the differential diagnosis of benign and malignant thyroid nodules is higher than that of conventional ultrasound. But both of them are of great significance in the diagnosis of thyroid nodule, so that the patients with thyroid disease can avoid unnecessary surgical treatment and have important diagnostic value in clinic.
【作者单位】：同济大学附属上海市东方医院医学超声科;
【基金】：浦东新区卫生行业科研专项课题(PW2013E-1) 上海市卫生和计划生育委员会科研课题(201440335) 上海市浦东新区卫生系统重点学科群建设资助(PWZxq2014-01) 同济大学附属东方医院青年项目(DFQH-Q16)
【分类号】：R445.1;R581

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