非典型多形性黄色星形细胞瘤的MRI及病理表现

发布时间：2018-03-02 14:12

本文选题：星形细胞瘤　切入点：磁共振成像　出处：《放射学实践》2015年01期 　论文类型：期刊论文

【摘要】：目的:探讨分析实质型多形性黄色星形细胞瘤(PXA)的临床、病理及影像学表现特征。方法:回顾性分析经病理证实的23例PXA患者的临床、病理及影像学资料,重点观察、分析11例实质型PXA的病变部位、病灶大小、瘤周水肿、恶变发生率及MRI信号特征。结果:11例实质型PXA患者中,发病平均年龄为(31.0±9.7)岁,9例(81.8%)病程≤1年;病变累及颞叶8例(72%),岛叶3例(27%),囊变发生率为72.7%(8/11);实质型PXA的瘤体体积中位数为7.2cm3;无水肿或轻度水肿3例(27%),中度水肿7例(64%),实质型PXA恶变发生率为9%(1/11)。实质型PXA MRI表现为实性肿块(伴或不伴囊变区),多数形态规则,边界清楚,实质部分T1WI呈等、低信号,T2WI呈高信号,瘤周水肿较轻,增强扫描呈明显较均匀或不均匀强化,邻近脑膜一侧强化显著。结论:实质型PXA的病程较短,肿瘤体积较小,恶性程度较低,MRI表现有一定的特征性,手术切除预后较好。
[Abstract]:Objective: to investigate the clinical, pathological and imaging features of parenchymal xanthomorphic astrocytoma (PXA). Methods: the clinical, pathological and imaging data of 23 patients with PXA proved by pathology were retrospectively analyzed. The lesion location, lesion size, peritumoral edema, incidence of malignancy and signal characteristics of MRI in 11 cases of parenchymal PXA were analyzed. Results the mean age of onset of 11 patients with parenchymal PXA was 31. 0 卤9. 7 years (9 / 81.8)). There were 8 cases of temporal lobe involvement and 27 cases of insular lobe involvement. The incidence of cystic degeneration was 72.7% and 8 / 11%. The median volume of solid PXA was 7.2 cm ~ 3. There were 3 cases with no edema or mild edema, 7 cases with moderate edema, and 7 cases with moderate edema. The incidence of solid PXA malignancy was 9 / 1 / 110.The incidence of parenchymal PXA MRI was 1 / 11. It is now solid mass (with or without cystic lesions, most of which are regular in shape. The boundary was clear, the parenchymal part showed iso-intensity on T _ 1WI, high signal on hypointense T _ 2WI, slight edema around the tumor, obvious homogeneous or uneven enhancement on enhancement scan and obvious enhancement on adjacent meninges. Conclusion: parenchymal PXA has a shorter course of disease and smaller tumor volume. The MRI findings of lower malignant degree have some characteristics, and the prognosis of surgical resection is better.
【作者单位】：广州市第一人民医院放射科;
【基金】：广州市科技计划项目(2014J4100071)
【分类号】：R445.2;R739.4

【参考文献】